JESSICA R. HOMAN, M.B.A.
STRATEGIC HEALTHCARE & OPERATIONS EXECUTIVE | GROWTH | TRANSFORMATION | OPTIMIZATION
SUMMARY
Visionary enterprise leader with 20+ years driving large-scale organizational strategy, operational transformation, and
strategic growth within one of the nation’s top academic medical centers. Operates at the VP level, translating strategy into
execution, transforming complexity into clarity, modernizing operations, and leading high-performing teams across
research, clinical, HR, and commercial domains.
Enterprise Leadership Snapshot:
• VP-level oversight: $500M portfolio | 3,000+ FTE | 20+ departments
• Unique Executive leadership in Research, Clinical Operations, Human Resources, and Commercial Strategy
• Proven success driving AI-enabled transformation, workforce optimization, and cultural alignment
CORE EXPERTISE
Operations & Strategy: Enterprise Program Management • Revenue Growth • Scalable Operating Models • Lean Six Sigma
• Change Management • Business Consulting • Budgeting & Forecasting • Commercial Strategy • Organizational Design
Digital & Analytics: Generative AI • Process Automation • Workflow Redesign • KPIs • Digital Transformation Strategy
Leadership & People: C-Suite Advising • Stakeholder Engagement • Talent Development • Culture Transformation
JESSICA R HOMAN CONSULTING LLC – Minneapolis, MN & Remote
Founder & Principal | Sept 2025 - Present
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Provide fractional VP-level strategy, operations, and people leadership for organizations that need experienced
guidance to stabilize, scale, or navigate complex transitions.
Support founders and CEOs as a strategic and operational partner, clarifying priorities, strengthening execution,
and creating the structures and workflows teams need to perform at a higher level.
Lead strategic initiatives involving new program development, operational redesign, culture and team
effectiveness, and the adoption of practical AI tools that improve learning, planning, and daily operations.
Offer executive and chief of staff-style coaching that equips leaders with clearer communication, stronger decisionmaking, and the ability to lead confidently through growth and change.
MAYO CLINIC – Rochester, MN | June 2004 – October 2025
Vice President, Research Operations & Strategy (Administrator, Research Services) | Sept 2020 – Oct 2025
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Executive leader for research and clinical practice operations in Oncology, Radiation Oncology, Urology, OBGYN, and ENT.
Oversight of $500M+ in grants and contracts, 350 staff, and 170 faculty/scientists.
Architected and launched a 5-Year Oncology Research Transformation Strategy, focused on doubling trial
accrual and extramural research funding, accelerating translation of discoveries into therapies.
Integrated research and clinical operations using AI-driven workflow design, cutting trial activation time by
60% and strengthening cross-disciplinary coordination.
Directed financial portfolio optimization and growth, increasing external funding by 25% through targeted gap
analyses, new grant strategies, and diversification of scientific leadership pipelines.
Championed translational science initiatives, moving discovery into practice-changing patient care and
securing long-term programmatic sustainability.
Advanced donor and philanthropic engagement, aligning institutional priorities with benefactor interests to
increase innovation funding by 30%.
Mentored and developed emerging leaders, fostering organizational resilience, accountability, and succession
readiness across multi-site teams.
Vice President, Provider Relations & Commercial Strategy | Sept 2016 – Sept 2020
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Directed enterprise-level external commercialization strategy through the Mayo Clinic Care Network and for-profit
consulting arm, partnering with executives, boards, and physician leadership to expand Mayo’s global footprint and
optimize commercial value.
Managed Mayo brand & strategic partnerships with 54 national and international health systems,
generating over $5M+ annually in incremental revenue.
Built and scaled the Education portfolio into the #1 valued offering utilized by 95% of members,
designing programs for global partners to reduce clinical variation and improve patient outcomes.
Designed and implemented a Collaborative Learning Model, embedding accountability, performance
metrics, and shared standards across national partner sites.
Leveraged AI-driven analytics and digital dashboards to monitor client outcomes, identify growth
opportunities, and ROI for consulting engagements.
Led physician engagement and well-being initiatives, securing funding for leadership development, burnout
prevention, and cultural alignment programs.
Vice President, Clinical Practice Operations – Surgical & Medical Specialties | May 2012 – Sept 2016
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Senior operational leader across surgical and medical specialties (Orthopedics, Urology, OBGYN, ENT,
Plastics, Ophthalmology, Surgery, PMR) generating $48M in revenue and $23M NOI. Oversight of 270+
employees and 82 physicians across multiple sites, accountable for care model alignment and access
growth.
Designed and implemented scalable operating frameworks supported by data analytics and forecasting,
expanding patient access by 30% and reducing clinical variation.
Optimized operating room (OR) with block utilization and transparency metrics, improving on-time starts by 40%
and increasing procedural throughput.
Partnered with physician and administrative leaders to redesign staffing models, organizational design,
and HR processes for efficiency and consistency across clinics.
Developed cross-functional teams with key stakeholders to assess workforce alignment, care delivery models,
and market opportunities to support expansion and sustainability.
Executive Director, Human Resources & People Strategy – Mayo Clinic & Health System | June 2004 – May 2012
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Executive leadership for human capital strategy supporting enterprise shared services, surgical departments, and
Mayo Clinic Health System operations. Oversight of 4500+ FTEs, 26 HR professionals, and $5M budget. Partnered
directly with the c-suite to design, align, and implement workforce, compensation, and cultural strategies.
Served as principal HR advisor to C-suite executives (CEO, COO, CFO, CHRO, CLO) on succession planning,
compensation redesign, and organizational structure.
Implemented HRIS and workforce analytics, reducing time-to-fill by 25 days, lowering voluntary turnover to
9% and enhancing visibility into talent pipelines.
Elevated physician satisfaction from 25% to 75% in one year by integrating physician voices in executive
decision-making. Strengthened trust and collaboration across hospitals and ORs while cultivating a culture of
engagement and inclusion.
EDUCATION & CERTIFICATIONS
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Master of Business Administration (M.B.A.) | Hamline University
Bachelor of Science (B.S.), Business Administration (HR/Marketing Minors) | Minnesota State University-Mankato
Instructor - Health Care Administration | Mayo Clinic College of Medicine and Science
Senior Professional in Human Resources (SPHR) | HRCI
Lean Six Sigma | Kaizen | Quality Academy | Mayo Clinic
Center for Creative Leadership | Alumni Leadership Development
