Rubén Javier López

RUBÉN JAVIER LÓPEZ ADDRESS: IBSENS GATE 58, BERGEN, (NORWAY) SUMMARY Biologist with a strong background in microbiology and molecular biology, with experience in bioinformatics and biological data analysis. MAIN SKILLS Molecular Biology – NGS (Illumina, Nanopore, PacBio) – PCR & Nucleic Acids isolation – Genome assembly and annotation (SPADES, Flye, Prokka, PGAP…) – Transcriptomics & Differential Gene Expression (DESeq2, R…) – Microbiome & Metagenomics (QIIME2, DADA2, Phyloseq, Mia…) – Communication skills – Linux & Command line tools – MacOS – International collaborations – Student supervision RELEVANT PROFESSIONAL EXPERIENCE FREELANCE BIOINFORMATICIAN • 2025-CURRENT Analysis of (micro)biological source data – Assembly and annotation of microbial genomes - Genetic mining (BLAST, UniProt, Pfam, MEROPS, etc.) – Microbiome & Metagenomics – Differential gene expression. PHD FELLOW •UNIVERSITY OF BERGEN •- DNA and RNA purification from bacteria – NGS (Illumina, PacBIO, Oxford Nanopore) - DNA-seq analysis – Illumina library preparation - Genome assembly – Gene mining – Comparative Transcriptomics – Comparative Proteomics. RESEARCHER •UNIVERSITY OF BERGEN •-. DNA and RNA purification from bacteria – NGS (Illumina, PacBIO, Oxford Nanopore) - DNA-seq analysis – Genome assembly – Gene mining – Cloning – PCR – Student supervision. - HTTPS://ORCID.ORG/- - HTTPS://WWW.LINKEDIN.CO M/IN/RJAVIER-LÓPEZ/ RESEARCHER (COLLABORATION) • GADE LABORATORY FOR PATHOLOGY, CENTRE FOR CANCER BIOMARKERS (CCBIO). HAUKELAND UNIVERSITY HOSPITAL •-. Biostatistics - Microbiome and Mycobiome data analysis - Qiime2 – R – Phyloseq. RESEARCH TECHNICIAN (BS) • BREAST CANCER RESEARCH• INCLIVA •-. RNA extraction from frozen tissue samples - DNA extraction from human blood - Cell culture and cell lines handling and maintenance - Nucleic Acids electrophoresis. RESEARCH TECHNICIAN (BS) • IVIA •-. Biochemical analysis of vegetal products - HPLC - PCR - DNA isolation. QUALITY TECHNICIAN • CALPDÉNIA • 2007 Hazard analysis and critical control points (HACCP) plan implementation. LAB TECHNICIAN • AFRIVAL • 2006 Microbiological analysis of goat and cow milk - Biochemical tests - Microbiological agar culture media preparation. RELEVANT EDUCATION AND DATE OF EARNED DEGREE PHD IN MICROBIOLOGY • 2025 • UNIVERSITY OF BERGEN MSC IN MICROBIOLOGY • 2018 • UNIVERSITY OF BERGEN POST DEGREE IN MEDICAL GENETICS • 2010 • UNIVERSITY OF VALENCIA UNIVERSITARY EXPERT IN FOOD BIOTECHNOLOGY • 2010 • UNED BACHELOR IN FOOD SCIENCE AND TECHNOLOGY• 2006 • UNIVERSITY OF VALENCIA BACHELOR IN BIOLOGY • 2004 • UNIVERSITY OF VALENCIA SCIENTIFIC PUBLICATIONS “Transcriptomic and Proteomic Insights into Feather Keratin Degradation by Fervidobacterium” Authors: Rubén Javier-López, Mélodie Kielbasa, Jean Armengaud and Nils-Kåre Birkeland. DOI: https://doi.org/10.3389/fmicb- Date: 04/2025 “Comparative genomics of Fervidobacterium: a new phylogenomic landscape of these wide-spread thermophilic anaerobes” - HTTPS://ORCID.ORG/- - HTTPS://WWW.LINKEDIN.CO M/IN/RJAVIER-LÓPEZ/ Authors: Rubén Javier-López, Natia Geliashvili and Nils-Kåre Birkeland. DOI: https://doi.org/10.1186/s--x Date: 2024/12 “Degradation of keratin compound residues by thermophilic bacteria with keratinase activity” Authors: Akzhigit Mashzhan; Rubén Javier-López; Aizhan Talipova; Aida Kistaubayeva DOI:-/bb.2024.v100.i3.08 Date: 2024/09 “Caldanaerobacter subterraneus subsp. keratinolyticus subsp. nov., a Novel Feather-Degrading Anaerobic Thermophile.” Authors: Akzhigit Mashzhan; Aida Kistaubayeva; Rubén Javier-López; Akerke Bissenbay; Nils-Kåre Birkeland. DOI: https://doi.org/10.3390/microorganisms- Date: 2024/06 “Polycladomyces zharkentensis sp. nov., a novel thermophilic cellulose-and starch-degrading member of the Bacillota from a geothermal aquifer in Kazakhstan” Authors: Akzhigit Mashzhan; Aida Kistaubayeva; Rubén Javier-López; Ulzhan Bissenova; Akerke Bissenbay; Nils-Kåre Birkeland. Date:2024/02 DOI: https://doi.org/10.1099/ijsem- “Fervidobacterium pennivorans subsp. keratinolyticus subsp. nov., a Novel Feather-Degrading Anaerobic Thermophile” Authors: Rubén Javier-López; Edoardo Mandolini; Munavvara Dzhuraeva; Khursheda Bobodzhanova; NilsKåre Birkeland. Date: 2022/12 DOI: https://doi.org/10.3390/microorganisms- “Analysis and Characteristics of Thermal Springs in Kazakhstan” Authors: Akzhigit Mashzhan; Rubén Javier-López; Aida Kistaubayeva; Irina Savitskaya; Nils-Kåre Birkeland Date: 2021/10 DOI: https://doi.org/10.1007/-_6 “Analysis of Salivary Mycobiome in a Cohort of Oral Squamous Cell Carcinoma Patients From Sudan Identifies Higher Salivary Carriage of Malassezia as an Independent and Favorable Predictor of Overall Survival” Authors: Nazar Mohamed; Jorunn Litlekalsøy; Israa Abdulrahman Ahmed; Einar Marius Hjellestad Martinsen; Jessica Furriol; Rubén Javier-López; Mariam Elsheikh; Nuha Mohamed Gaafar; Luis Morgado; Sunil Mundra et al. Date: 2021/10 DOI: 10.3389/fcimb- “Metagenomics and Culture-Based Diversity Analysis of the Bacterial Community in the Zharkent Geothermal Spring in Kazakhstan” Authors: Mashzhan A.S.; Rubén Javier-López; Aida Kistaubayeva; Irina Savitskaya; Nils-Kåre Birkeland Date: 2021/08 DOI: 10.1007/s- - HTTPS://ORCID.ORG/- - HTTPS://WWW.LINKEDIN.CO M/IN/RJAVIER-LÓPEZ/ OTHER SKILLS Languages: Spanish: native. Valencian: native. English: fluent, professional level, spoken and written. Norwegian: basic knowledge. Driving License: B1 - HTTPS://ORCID.ORG/- - HTTPS://WWW.LINKEDIN.CO M/IN/RJAVIER-LÓPEZ/