John Turman

 John Wesley Turman Contact Tel :- E-mail :- Key Skills Researcher and scientist with a background in organic chemistry. An industry experienced professional who excels at problem solving, forging relationships, and enjoys the challenge of optimizing processes to accomplishing specific goals as efficiently as possible. A history of adapting quickly to new roles and bringing a contagious sense of optimism and work ethic to a team Education MS in Chemistry, cum laude - University of North Carolina Wilmington Thesis Title: Targeted Chemotherapy: Design and Synthesis of a Biotin Conjugated Minor Groove Binder Capable of Selective DNA Damage BA in Chemistry - University of North Carolina Wilmington Professional Experience Biogen-Cambridge, MA- Associate Scientist II Focused on the design and synthesis of small molecules for the treatment of CNS related diseases Balanced many projects simultaneously, researching synthetic routes and procurement of chemicals and lab supplies from various suppliers Optimized processes for parallel synthesis and laboratory robotics to increase efficiency and productivity Developed SAR and optimized molecules to increase potency and properties of early HTS hits with the goal to transition programs from Exploratory to Lead ID Designed and prioritized individual molecules and libraries based on compound enumeration and docking with X-ray structures PepsiCo- Bradenton, FL 2016 R&D QA Engineer Established connections with suppliers to determine ingredient origins and ensure identity preservation Coordinated with product developers to formulate and source ingredients Operated across multiple brands to acquire Non-GMO Project Verification for specific products GlaxoSmithKline- RTP, NC - Research Chemist Intern Synthesized a library of small molecules designed as HIV Integrase Inhibitors as a member of the HIV DPU Developed HPLC methods to identify and remove impurities from final products, on analytical and preparative scales Produced over 150 final compounds for biological testing Optimized multi-step syntheses on scales ranging from 1 mg to 1 Kg UNC Wilmington - Graduate Research Assistant Designed, synthesized and tested site specific DNA alkylating agents targeted to cancer cells Cultured cells and prepared DNA solutions for experiments with synthesized molecules Maintained all instruments in the lab and prepared buffers, mobile phases, and solutions with pH meter and UV/VIS Managed inventory and supplies for the lab Synthesized over 100 molecules for multiple projects using NMR, LCMS, TLC and FT/IR to confirm the identity Lead a team of undergraduate and graduate chemists to complete all projects on time and aid PI in obtaining over $100,000 in grants UNC Wilmington - Graduate Teaching Assistant Lab Instructor for CHM 101 and 102 Reinforced concepts from general chemistry learned in class and introduced students to basic laboratory techniques UNC Wilmington - NMR Technician Maintained and calibrated instrument daily Trained and educated students on NMR theory and use Ran NMR samples for Advanced Organic Lab CVS/ Pharmacy- Wilmington, NC- Pharmacy Technician PTCB Nationally Certified Pharmacy Technician Knowledge of Pharmaceuticals and Insurance Policies Publications/Patents Gabbita SP, Johnson MF, Kobritz N, Eslami P, Poteshkina A, Varadarajan S, Turman J, Zemlan F, Harris-White M. Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model.PLoS ONE 10(10):e-. doi:10.1371/journal.pone- (2015) WO -  WO - WO - Additional Scientific Engagement Chemistry Conferences Boston Society HT-ADME Conference Cambridge, MA June 2019 17th Annual BU-CMD Symposium- Molecular Discovery: From Chemical Synthesis to Biological Applications Boston, MA June 2019 The Practical Application of Artificial Intelligence in Drug Discovery Boston, MA December 2018 Laboratory Robotics Interest Group New England Seminar and Exhibition in Boston, MA October 2018 1st Alpine Winter Conference on Medicinal and Synthetic Chemistry in St. Anton, Austria January 2018 Pfizer Symposium on Drug Discovery Harvard University Cambridge, MA October 2017 Moderator at the 6th World Congress on Medicinal Chemistry and Drug Design in Milan, Italy June 2017 Presented graduate research at S.E.R.M.A.C.S. Atlanta, GA Nov 2013 Training How to Succeed in Drug Discovery: Insight from Medicinal Chemists January 2019 Biogen Mentorship Program- Mentee- Executive Coaching SciFinder training for advanced users December 2018 3-day Biogen Drug Discovery Course November 2018 Spinal Muscular Atrophy: Novel Approaches for Treatment September 2018 American Chemical Society CNS webinar July 2018 Residential School on Medicinal Chemistry and Biology in Drug Discovery, Drew University June 2018 Maestro 11 by Schrodinger Training June 2018 Chemspeed Solid dispensing webinar on laboratory robotics March 2018 Mining gene and disease associations with Open Targets for improved drug target identification June 2017 Tangling with tau and other AD proteins – the need to know the molecules May 2017 ACD Labs Advanced Training February 2017 Undergraduate Research Synthesis of TNFα inhibitors for the treatment of Alzheimer’s disease Spring 2012 Ocean Plastics on Wrightsville Beach Spring 2012 Volunteering Southeastern US Regional Science Fair Judge NC Science Olympiad Judge