Isha Gupta

Isha Gupta 56, Upper fort, Aligarh, U.P., 202001 --26 |Female https://www.linkedin.com/in/isha-gupta-70946b153/ As a Bioinformatics Research Analyst, I possess a strong focus and skillset along with data processing, analysis, and insight generation experience. Proficient in developing and optimising pipelines using various tools and platforms. I am always eager to explore and analyze intricate datasets. Seeking a challenging position where I can put my abilities to use and contribute to data-driven decision-making. Work Experience International Centre for Genetic Engineering and Biotechnology (ICGEB) (Apr’24-present) Project Associate Antimicrobial Resistance (AMR) Research Conducted genomic analysis of ESKAPE pathogens on AmpC β-lactamases and analyze their phylogenetic relationships. Scientific writing CSIR Institute of Genomics and Integrative Biology (IGIB) (Nov'23-Mar’24) Project Associate II GitHub: Managed and collaborated on bioinformatics projects using version control. Snakemake: Developed and optimized workflows for bioinformatics analysis to enhance efficiency and reproducibility. Docker & Conda: Implemented containerization and environment management using Docker and Conda, ensuring consistent execution of bioinformatics workflows across platforms. T-CAG LifeSciences Pvt Ltd, New Delhi (Jan’23-Nov’23) Bioinformatics Analyst Utilize bioinformatics tools and techniques to analyze large-scale biological data Develop and execute pipelines for processing, analyzing, and visualizing data Communicate findings and results effectively to team members through presentations. GD Research Center, Hyderabad, Telangana (Jan 20-Aug 21) Associate Analyst Data retrieval, management, classification, report creation, and statistical analysis Data analysis to uncover valuable insights and knowledge. Contributed to team meetings by actively participating in discussions on research progress. Skills & Proficiencies Proficient in retrieving, transforming, classifying, and manipulating data information using various tools and programming languages (e.g., Python, R, Excel) Proficient in using visualization tools (e.g., RStudio, Tableau) Skilled in using Microsoft Excel for data analysis, spreadsheet creation, and task automation. Familiarity with machine learning algorithms and their application in data analysis Strong analytical and problem-solving skills, with the ability to identify data-related challenges and develop effective solutions. Proficient in using various bioinformatics tools and platforms, including Galaxy and Linux, for developing and optimizing WGS pipelines. Proficiently conducted amplicon-based 16S rRNA analysis, elevating data-driven insights in microbiological research. Proficient in Python programming with a focus on biological data analysis, visualization, and machine learning. Skilled in working with various biological data formats and utilizing libraries such as Biopython, NumPy, Pandas, and scikit-learn. Experienced in data manipulation, statistical analysis, and hypothesis testing using Python. Proficient in creating visualizations and interactive plots using Matplotlib, Seaborn, Plotly, NetworkX. PUBLICATIONS AmpC β-lactamases: A Key to Antibiotic Resistance in ESKAPE Pathogens (to be published) Protein Engineering Methods for the Design of Protein Therapeutics Machine Learning for Drug Designing Educational Background M.Tech Bioinformatics Amity Institute of Biotechnology, Noida CGPA: 9.24/10 B.Tech Bioinformatics Amity Institute of Biotechnology, Jaipur CGPA: 8.12/10 ( 19-May'23) Co-curricular Activities/Participation Achieved 1st position in March Past at ( 19-May'20) Internship & Academic Projects Military Training Camp at Amity University, Jaipur. Successfully completed military training camp at Amity University, Rajasthan (2019). Attended multiple workshops conducted at Vitiligo Research, Amity University, Noida (Jun'22-Jul'22) Differential expression analysis RNA-seq Analysis of Human Endometrium, Amity University, Noida (Oct'22-Dec'22) Genomics and Molecular biology Analyze and interpret the results obtained from the differential expression analysis and functional enrichment analysis. Summarize the findings and prepare reports or presentations (Jun'19-Jul'19) Rajasthan University, Jaipur Provided support in analyzing and interpreting biological data. Performed literature searches and compiled pertinent information for analysis. Jamia Milia Islamia, New Delhi, India -Department of (Jun' 18-Jul'18) Biotechnology Molecular Drug Designing Amity University, Rajasthan (2016 - 2019). Software/Tools “Role of Microbes in Industrial Revolution” MS Office Visualization and analysis: RStudio, Tableau Bioinformatics tools and databases: NCBI, BLAST, UniProt, PDB, MUSCLE, T-Coffee. Next-generation sequencing data analysis: Fastqc, trimmomatic, QUAST, BUSCO, MeDuSa, Bowtie, SAMtools, Pilon Genome assembly and annotation: SPAdes, Megahit, IDBA, VELVET, Unicycler and Prokka Phylogenetic Analysis: PHYLIP, MEGA7 Chemical Modeling and Analysis: Chemsketch, ADMET, Open Babel, Chimera, Protparam, Peptide Cutter Languages English, Hindi, German, Spanish Actively participated in Sangathan held at Amity University, Rajasthan (2016 - 2019). Took part in a three-day workshop on “Advanced Computer-aided Drug Design and Computational Biology” organized by Schrodinger at Amity University, Jaipur (2019). Presented a poster on “Reverse Vaccinology as a Solution for generating vaccine leads for NTMs” at NIIT Jaipur (2019). Participated in a workshop on “Bioinformatics and System Biology” at Birla Institute of Scientific Research, Jaipur (2019). Presented a poster on “Informational Theory of Biological Sequences and its Application” at the three-day international conference on held at Jaipur National University (2018). Presented a model on Waste Transformation (2017). Programing Languages Python, R and bash scripting