CHRISTIAN TYLER STACKHOUSE, PHD
464 Townsend Street | North Wilkesboro NC, 28659 | --LinkedIn: www.linkedin.com/in/christian-stackhouse-phd-a8b82819/
Publication Profiles: NCBI - https://bit.ly/3KHIQUe Scholar - https://bit.ly/3IZnXEG
Objective Statement: Biomedical scientist & business professional with over a decade of leadership and
supervisory experience in translational sciences, grant writing, commercialization, & strategic consulting.
Skills: Expert in all MS Suite apps | Adobe suite | SalesForce | SharePoint | Teams | Slack | Zoom | AWS
| high-performance computing | big data manipulation & secure transfer | R programming | Matlab |
SPSS | SAS | Python | BASH scripting | Git architecture | Java script | HTML | CSS | semantic/linked
data formats (RDF | OWL | SPARQL) | subversion software | modeling/forecasting | data visualization |
program management | product launch strategy | GTM | team leadership & management | client
engagement | lead generation | scientific communication | communication & engagement | marketing
strategy | market research | competitive intelligence.
Therapeutic Areas & Scientific Expertise:
Hematology-oncology | neuroscience | basic/laboratory sciences | drug discovery & development | RNA
therapeutics | cell & gene therapy | ASOs | RNAi | CRISPR/Cas | immune-oncology | radiation oncology
| pre-clinical model development | marine sciences | NGS | single-cell studies | environmental sciences
| epigenetics | crops sciences | bioinformatics | biostatistics | natural products chemistry | biochemistry
| biotechnology.
PROFESSIONAL EXPERIENCE
LiteBoat: Coastal Rowing USA
Independent Sales Consultant
Direct sales of LiteBoat's full line of light, stable, easy to row shells
Oct 2023 - Present
• Responsible for generating, tracking, and converting leads to opportunities for direct sales in the
Southeastern U.S. and Southern Central U.S. market regions
• Utilize SalesForce software to manage leads, track opportunities, and convert to closed sales
• Promote the LiteBoat brand through direct client engagements, social media engagements, and as a
LiteBoat owner through demonstrations & competition involvement
Pineview Farms Consulting
Private Consultant and Solutions Specialist
Providing research developed, excellence drive solutions to optimize performance
Mar 2023 - June 2025
• Providing solutions & services in: commercialization strategy, business/corporate growth strategy,
business operations solutions, strategic partnerships, technical due diligence, audience/community
engagement/content, data security & integrity, Hit-to-Lead (H2L) optimization, and subject matter expertise
• Scientific Communications, Grant Writing Support, Publication Support, Public Engagement/Engagement
Strategy, Data Analysis, Data Visualization, Data-driven Insights& Primary Research Support
• Generating sustainable, scalable, solutions to achieve corporate visions and to discover new revenue
streams or growth opportunities including optimization of existing resources
SEDULO GROUP, Global Life Sciences Division
Client Engagement Manager – Life Sciences Strategy Consultant
Jan 2022 – Mar 2023
Full-service strategy & competitive intelligence consultant for life sciences/pharmaceutical industries
• Supervised multiple concurrent teams of analysts, consultants, contractors, and executive team members
• Managed diverse portfolio >$1M USD including new & established clients in Pharmaceuticals, Medical
Devices, Biotechnology, & Biomedical Contract Services Industries across Global Life Science Sectors
• Client Engagement & project supervision for Product Launch, Commercialization, Strategic Marketing,
Goto-Market (GTM) Strategy, Regulatory Affairs/Submissions, Reimbursement Strategies, Payer & HCP
Adoption, Primary Research, & Product Management including Life Cycle Management (LCM)
• Authored & Published Public Content for Omni-channel marketing & Targeted BD Campaigns,
Promotional Marketing, Public Engagement, and to Support Corporate Growth Goals in collaboration with
C-Suite & Senior Leadership
• Authored comprehensive White Papers on the State of the Field for: Gene-editing Technologies, Cell based
Therapies, and Rational Drug Discovery & Development across Health and Global Life Sciences
• Owned Projects as Point of Contact for Client Engagement with Senior Leadership teams including Market
Managers, Division Directors, Vice Presidents of Business Development & Licensing, & CXO Executives
• Wrote and managed Independent Contractor Agreements for CI & Primary Market Research
• Responsible for Full Project Management including Resource Management, Budgeting, Directing Primary
& Secondary Research, Synthesis & Presentation of Deliverables, Leading on-site Client Workshops and
Product Launch Strategy Simulations, Contract Retention & Expansion, Team Training, Mentoring, and
Performance Reviews
• Synthesized information and data across sources to generate Business Intelligence transformed into
Actionable Insights to build Strategic Plans for Product Launch, Market Disruption/Penetration, Strategic
• Partnerships, Portfolio Expansion/Diversification, Product LCM, Marketing/Engagement, Regulatory,
Reimbursement, Pricing Strategies, Business Development, Operations, Marketing, and Growth Strategies
• Independently streamlined internal Operations and Optimized Workflow Efficiency representing a >60%
reduction in effort/cost with improved Quality, Fidelity, & Data-driven Decision-Making capabilities
• Support Business Growth as a Subject-Matter Expert (SME) in Pitch Meetings & Contract Scoping
• Operational Optimization: Formulated & Implemented SOPs for Data Governance, Systems Integrations,
Data Security, and Risk Management
Duke University School of Medicine
Postdoctoral Fellowship in Pediatric Hematology-Oncology
RNA-based drug discovery and design for pediatric sarcomas & adult glioma
Jan 2021 – Feb 2022
• Inventor on 3 Provisional USPTO filings for RNA-based Therapeutic Products and Hit to Lead
Methodologies (at least one converted to full application)
• Conducted Technical Due Diligence & Contract Negotiations with partners for Product Development,
Ownership, Cost/Resource Sharing, and Out Licensing
• Certified as a Research Animal Coordinator responsible for Training of Laboratory Staff on Responsible
Conduct of Research (RCR), Research & Animal Ethics, Developing & Performing Experimental Protocols,
and ensuring Regulatory Compliance with AAALAC, IACUC, OSHA, and IRB
• Supervised / managed 5 Direct Reports as Lead Investigator & Mentor for interdisciplinary team including
research scientists, lab managers, research support staff, & graduate/undergraduate students
• Grant writing Principal Investigator & Young Investigator Award Recipient from Alex's Lemonade Stand
• Grant Recipient from Children's Miracle Network Hospitals: Trainee Award
University of Alabama at Birmingham
Graduate Research Associate
July 2014 – Dec 2020
Ph.D. in Neuroscience, Neuro-Oncology Program
Long non-coding RNAs in glioblastoma multiforme therapy resistance
• Principal Investigator on UAB Radiation Oncology Intramural Pilot Grant
• Published 4 first-author manuscripts with ongoing contributions to numerous scientific publications in
industry- leading research journals including Nature Communications, The Journal of Clinical
• Investigation, Cancer Research, Journal of the American Association of Nurse Practitioners, Cells, and
others.
• Developed novel pre-clinical Patient-derived Models of acquired Therapy Resistance being utilized by the
global Neuro- Oncology Research Community and which have Generated New Sources of Research
Revenue (>$5M USD in NIH Grants & other Funding), multiple High-Impact Peer-Reviewed Publications,
and a growing number of USPTO Filings
• Supervised team and Lead Principal Investigator on Hit-to-Lead Discovery of therapeutic targets
overcoming resistance in Relapsed/Refractory tumors
• Established Intramural, Intercollegiate, and International Collaborations for RNA Therapeutics Research
• Developed a novel, TME agnostic assay for glioblastoma on an FDA-approved CLIA-certified molecular
assay platform
• Wrote grants for, Founded, & Directed an Interdisciplinary Team comprised of multi-focal Subject Matter
Experts & University Leadership
• Co-Developed & published Machine Learning (ML) algorithms for rapid, robust feature selection
• Led a Clinical Informatics Team investigating Racial Disparities and Co-morbidities for COVID-19
patients at UAB Hospitals with highlights publicized by the American Medical Informatics Association
(AMIA) & UAB Public Relations
• Presented at 12+ International Conference Oral and Poster abstracts within prestigious national &
international research communities comprised of Industry Leaders, Key Opinion Leaders (KOLs), Clinical
Practitioners, and Public Advocates
• Authored a Textbook Chapter on Patient-derived Models for Translational Research Applications
University of North Carolina at Chapel Hill
Staff Research Scientist and Lab Manager
Marine Sciences Department
Oct 2013 – July 2014
• Responsible for project management, equipment ordering & maintenance, reporting & compliance for use
of radioactive materials, contracting with service providers, ordering & project budgeting, authoring SOPs
& laboratory protocols, and grant/manuscript writing support
• Conducted independent wet lab and bioinformatics research on phytoplankton populations including net
primary production & environmental meta-transcriptomics in the Neuse River Estuary presented at the
Sea Grant Research Symposium & UNC Scientific Computing Research Symposium
• Provided research support, training, and mentorship to 3 graduate & 6 undergraduate researchers
EDUCATION AND ADDITIONAL INFORMATION
Durham, NC
2021 – 2022
Duke University
Postdoctoral Associate in Pediatric Hematology/Oncology
Research Animal Coordinator
2014 – 2020
University of Alabama at Birmingham
Birmingham, AL
PhD Neuroscience - Graduate Biomedical Sciences Program
Neuro-oncology Training Program, Brain Tumor Animal Core
2009 – 2013
North Carolina State University
B.S. in Biochemistry; Minor in Biotechnology
Raleigh, NC
Summa cum Laude, University Honors, Biochemistry Honors
• Research Assistant: NCSU Crop Science Department, Nov 2011 - May 2013
• Research Assistant: NCSU Genetics Department, June 2011 - Nov- - 2009
North Carolina School of Science and Mathematics
Durham, NC
Science Catalyst Award – State of NC Educators Conference Presentation, NASA Outreach Award
Publications
1. Christian T. Stackhouse. The Potential Roles and Applications of the long non-coding RNAInteractome in glioblastoma Etiology and Treatment. ESMED Medical Research Archive.
Publication Accepted June 2025.
2. Nassour-Caswell LC, Kumar M, Stackhouse CT, Alrefai H, Schanel TL, Honan BM, Beierle AM, Hicks
PH, Anderson JC, Willey CD, Peacock JS. Altering fractionation during radiation overcomes radioresistance in patient-derived glioblastoma cells assessed using a novel longitudinal radiation
cytotoxicity assay. Radiother Oncol. 2024 Nov 21:110646. doi: 10.1016/j.radonc-. Epub
ahead of print. PMID:-.
3. Christian T. Stackhouse, Joshua C. Anderson, Zongliang Yue, Thanh Nguyen, Nicholas J. Eustace,
Catherine P. Langford, Jelai Wang, James R. Rowland IV, Chuan Xing, Fady M. Mikhail, Xiangqin Cui,
Hasan Alrefai, Ryan E. Bash, Kevin J. Lee, Eddy S. Yang, Anita B. Hjelmeland, C. Ryan Miller, Jake Y.
Chen, G. Yancey Gillespie, Christopher D. Willey. An in vivo model of glioblastoma radiation
resistance identifies long non-coding RNAs and targetable kinases. JCI Insight. 2022 Aug 22;7(16).
doi: 10.1172/jci.insight.148717. PubMed PMID:-; PubMed Central PMCID: PMC-.
4. Satoru Osuka, Dan Zhu, Zhaobin Zhang, Chaoxi Li, Christian T. Stackhouse, Oltea Sampetrean,
Jeffrey J. Olson, G. Yancey Gillespie, Hideyuki Saya, Christopher D. Willey, Erwin G. Van Meir. Ncadherin upregulation mediates adaptive radioresistance in glioblastoma. J Clin Invest. 2021;
131(6):e136098. https://doi.org/10.1172/JCI136098.
5. Stackhouse CT, Gillespie GY, Willey CD. Exploring the Roles of lncRNAs in GBM Pathophysiology
and Their Therapeutic Potential. Cells. 2020 Oct 28;9(11):E2369. doi: 10.3390/cells-. PMID:-.
6. Hodges JM, Stackhouse CT, Smith GL. The impact of provider training on patient education for
pediatric early food introduction. J Am Assoc Nurse Pract. 2021 Jan 8. doi: 10.1097/
JXX-. Epub ahead of print. PMID:-.
7. Stackhouse, C.T.; Rowland, J.R.; Shevin, R.S.; Singh, R.; Gillespie, G.Y.; Willey, C.D. A Novel Assay for
Profiling GBM Cancer Model Heterogeneity and Drug Screening. Cells. 2019, 8, 702. PMID:-
PMCID: PMC- DOI: 10.3390/cells-
8. Stackhouse, C. T., Willey, C. D., & Gillespie, G. Y. Cancer Explant Models. In F. Bagnoli & R. Rappuoli
(Eds.), Current Topics in Microbiology and Immunology. Mar 20 2019. doi: 10.1007/82_2019_157 PMID:-
9. Katherine E. Savell, Nancy V. N. Gallus, Rhiana C. Simon, Jordan A. Brown, Jasmin S. Revanna, Mary
Katherine Osborn, Esther Y. Song, John J. O’Malley, Christian T. Stackhouse, Allison Norvil, Humaira
Gowher, J. David Sweatt, Jeremy J. Day. Extra-coding RNAs regulate neuronal DNA methylation
dynamics. Nature Communications, 2016; 7: 12091 DOI: 10.1038/ncomms12091
Presentations and Abstracts
April 4, 2023- AACR Annual Meeting Glioblastoma brain tumor-initiating cells are protected from
hypoxia when co-cultured with normal human astrocytes revealing a potential role for mitochondrial
transfer via tunneling nanotubes. Abstract 1273. Poster. DOI: https://doi.org/10.1158/-.AM-
November 1, 2022- ASTRO Annual Meeting Alternating Radiation Fractionations Overcome
Radioresistance in Patient-Derived Glioblastoma Cells. Abstract 2167 – Table 1. DOI:
https://doi.org/10.1016/j.ijrobp-
November 1, 2022- ASTRO Annual Meeting Deploying a Systems Biology Approach to Identify Drivers
of Radiation Resistance in Glioblastoma Multiforme (GBM) Patient-Derived Xenograft (PDX) Models.
DOI: https://doi.org/10.1016/j.ijrobp-
June 15, 2022- AACR Annual Meeting Therapeutic targeting of oncogenic long non-coding RNAs
utilizing antisense oligonucleotides. Abstract 5429. Virtual Poster and E-Talk.
July 1, 2021- AACR Annual Meeting IGF1/N-cadherin/b-catenin/Clusterin signaling axis can mediates
adaptive radioresistance in glioblastoma. Abstract 3078. Virtual Poster and E-Talk.
November 19-21, 2020- Society for Neuro-Oncology Annual Conference The roles of lncRNAs in GBM
radiation resistance and tumor recurrence. E-Talk.
November 4, 2020- NIH Patient Derived Models of Cancer Consortium Annual Meeting Understanding
How Radioresistance and Ischemic Tumor Environments Alter the Glioma Kinome. E-Talk.
October 25-28, 2020- Miami Beach, Florida ASTRO 62nd Annual Meeting Multi-omic exploration of
inherent and acquired radiation resistance of glioblastoma patient-derived xenografts. Oral Abstract.
June 22-24, 2020- Virtual Meeting – American Association for Cancer Research Annual Meeting
Long non-coding RNAs in glioblastoma tumor recurrence and therapy resistance. E-Poster.
June 19, 2020- UAB COVID-19 Data Science Hackathon Showcase COVID-19 Disease Burden and
Comorbidities in African American Patients at UAB. Oral Presentation.
November 22, 2019- Phoenix, AZ Society for Neuro-Oncology Annual Conference Long Non- Coding
RNAs in GBM Tumor Recurrence and Therapy Resistance. E-Talk and Poster.
November 20, 2019- Phoenix, AZ SNO EANO Brain Tumor Research Dinner Long Non-Coding RNAs in
GBM Tumor Recurrence and Therapy Resistance. Poster.
June 22, 2018- Copenhagen, Denmark 20th Annual Meeting of The Brain Tumor Epidemiology
Consortium Exploring the role of lncRNA in Radiation Resistances in a GBM-PDX Model of Tumor
Recurrence. Oral Presentation
March 1, 2017- Creation of an Analytical Platform for Integrative Molecular Profiling of Glioblastoma
Xenolines. American Journal of Clinical Pathology. https://doi.org/10.1093/ajcp/aqw191.037 Abstract.
May 13, 2016- 3rd Bi-Annual GBS/JHS Graduate Student Research Symposium Systematic
Characterization and Integration of Molecular Data from Patient-Derived GBM Xenoline Tumor
Panel to Explore Genomic and Gene Expression Abnormalities and Kinomic Profiles. Poster.
March 10, 2016- Graduate Research Days What the Semantic Web Can do for Personalized Cancer
Treatment: Glioblastoma multiforme. Oral Presentation.
April 9, 2015- CNC Retreat Novel 3’UTR Extensions of Neural Genes are Differentially Expressed with
Activity and Across Brain Regions. Poster and Lightning Talk.
November 19, 2014- UAB Rotation Poster Session Effect of HCN Channel Antagonist on GABAMediated Epileptiform Activity. Poster.
May 2014- UNC Chapel Hill Research Scientific Computing Seminar Integrating Eukaryotic and
Prokaryotic Plankton Community Transcriptomics into an Ecological Network Analysis of the Neuse
River Estuary. Poster
April 16, 2014- NC Sea Grant Research Symposium Integrating Eukaryotic and Prokaryotic Plankton
Community Transcriptomics into an Ecological Network Analysis of the Neuse River Estuary. Poster.
April 10, 2013- NCSU Undergraduate Research Symposium Novel Fungicide Bioassay of Leaf Surface
Compounds in Tobacco. Poster.
Volunteerism
- Co-Director of Brain Awareness Week promoting public education and awareness of basic
neurobiology/neuroscience concepts and health- Blazer Bolt for Brain Cancer 5K.
Volunteer/Student Ambassador for ROAR the Cure Annual Gala- NC Student Academy of Science
State Competition (NCSEF Region 3B) Volunteer STEM Judge. BSA Eagle Scout & Order of the Arrow
Brotherhood Member, UAB Graduate Student Government Secretary, NCSU Student Government Senator
Grants and Awards
Grants Received as Principal Investigator: $150,000: Alex’s Lemonade Stand Young Investigator Award +
$5,000 ALSF & Northwestern Mutual Resource Sharing Plan Supplement; $15,000: Children’s Miracle
Network Hospital’s Pediatric Trainee Research Award; $5,868: UAB Radiation Oncology Intramural Pilot
Grant; $1,500: Ireland Research & UAB Graduate Student Government Travel Scholarships.
Languages
Native English and conversational Spanish
Personal Interests
Rowing, swimming, coaching youth sports, hiking/backpacking, grilling on the Blackstone, gardening,
travel, reading science fiction, British television, licensed foster parent.
Publication Profiles
NCBI - https://bit.ly/3KHIQUe
Google Scholar - https://bit.ly/3IZnXEG
