Matthew Perry

Oncologists Patients Cancer Centers Oncology Researchers Cross­Disease Researchers seitin Knowledge um evitaitinIer QOPI OMH PQRS Certification The Informatics Market Exchange m Knowledgebase C o Guidelines utuF Accreditation Future Program Security ­ Entitlements ­ Policies – Preferences DB1 DB2 DB3 DB5 Native – Identical copy from source Harmonized Liaison Health Data ManagementTM Hadoop Cassandra Oracle Subset of DB2 Retrospective Analytics – Structured and unstructured data Limited Summarized Linked – Populations, cohorts Predictive Analytics Structured NLP – Unstructured documents and free text processed to derive structure Cleansed – Flexible dimensions: demographics, clinical criteria, etc. BI Conclusions Population Cohort (A) (B) Other... by ZIP by Biomarker Report Outputs Transformed Structured – Standardized AMH intake format DB4 Data Visualizations Cleansed PHI included Subset of DB2 Guidelines – Reconciliation of inaccurate, incomplete, and erroneous data Detailed Statistically De­Identified Detailed (A) (B) Other... Knowledge Linked – Patients EMPI – Practicioners MPI – Institutions, practices Controlled by REFERENCE TERMINOLOGIES NCI MetaThesaurus NCIt ICD­9 ICD­10 SNOMED CT RxNorm LOINC CPT UMLS Semantic Network Gene Ontology Other... Netezza Architecture Diagram Non­Oncology Practicioners Non­Oncology Institutions ASCO Personnel The Informatics Market Exchange DB1 DB2 DB3 DB5 Native – Identical copy from source Harmonized – Structured and unstructured data REFERENCE TERMINOLOGIES Liaison Health Data ManagementTM Subset of DB2 Limited Summarized Linked – Populations, cohorts Structured – Flexible dimensions: demographics, – Unstructured documents clinical criteria, etc. and free text processed to derive structure Cleansed Population (A) by ZIP Transformed Structured – Standardized AMH intake format PHI included Cleansed – Reconciliation of inaccurate, incomplete, and erroneous data Detailed Linked – Patients – Practicioners – Institutions, practices Netezza Retrospective Analytics Predictive Analytics NLP BI Conclusions Cohort (B) Other... by Biomarker Report Outputs DB4 Data Visualizations Subset of DB2 Guidelines Statistically De­Identified Detailed (A) (B) Other... Knowledge EMPI MPI Controlled by Ontology Extensions to Support Enhancements NCI MetaThesaurus NCIt ICD­9 ICD­10 SNOMED CT RxNorm LOINC CPT UMLS Semantic Network Gene Ontology Other... Oncologists Patients Cancer Centers Oncology Researchers Cross­Disease Researchers seitin Knowledge um ralucel C oM scitsong D QOPI OMH PQRS Certification m o Knowledgebase ai Accreditation Recruitment+ Security ­ Entitlements ­ Policies – Preferences Hadoop Cassandra Oracle Watson Architecture Diagram (Including Enhancements) Non­Oncology Practicioners Non­Oncology Institutions ASCO Personnel Data Flow Diagram NHIN Sources Oncologists • VA • EMRs • CMS • Practice Mgmt • CHIC • RAD/ONC Systems • DOD • SSA • Kaiser Perm • Regenstrief DB1 – Native DB1 DB3 S ASCO Sources • Membership • Publications • Repositories – HIPAA Limited Subset of DB2 Integrate Integrate DB4 – Statistically De­Identified Subset of DB2 Patients HDM LOGO DB5 Retrospective Analytics Predictive Analytics BI Conclusions Report Outputs Data Visualizations Existing Guidelines Knowledge Analyzed Legend Input Output HIPAA Limit Transform PLN/eru Cleanse Link/EMPI/MPI – Structured – Transformed – Cleansed – Linked DB2 tcurt – Harmonized – PHI Included De­identify Patient Claims Data Opt In/Out Program Registration Practice Connectors Analytics and BI Reports and Dashboards ASCO Data Scientists The Informatics Market Exchange Registry, data, application, and analysis monetization External Customers • Oncologists • Patients • Cancer Centers • Etc. External Customers • Practicioners • Researchers • Institutions • Etc. Patient Claims Data Opt In/Out Data Flow Diagram (Including Enhancements) NHIN Sources Oncologists Program Registration • VA • EMRs • CMS • Practice Mgmt Practice Connectors Analytics and BI Reports and Dashboards Guideline Manager Input Output ASCO Sources Molecular Diagnostics • Membership • CHIC • RAD/ONC Systems • Foundation Medicine • Publications • DOD • Repositories • SSA • Kaiser Perm • Regenstrief DB3 Reports and Dashboards External Customers • Oncologists • Patients – HIPAA Limited Guideline Manager • Cancer Centers • Molecular Diagnostics Subset of DB2 • Etc. Integrate HDM LOGO DB5 DB1 Transform HIPAA Limit Retrospective Analytics Predictive Analytics – Native PLN/eru Cleanse DB2 BI Conclusions ASCO Data Scientists tcurtS Link/EMPI/MPI – Harmonized Report Outputs – PHI Included Data Visualizations Integrate Existing Guidelines De­identify Knowledge DB1 Analyzed – Structured DB4 – Transformed – Cleansed – Statistically – Linked De­Identified Subset of DB2 Watson The The Informatics Informatics Patients Market Market Exchange Exchange External Customers • Practicioners • Researchers Institutions Legend • Molecular Diagnostics Registry, data, application, • Etc. and analysis monetization