Ebook - Example referencing
REFERENCES [ pg.
163 ]
REFERENCES
1
Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition
Examination Survey-. Arthritis Rheum. 2011;63(10):-
Kramer HM, Curhan G. The association between gout and nephrolithiasis: the National Health and Nutrition Examination Survey III,-. Am J Kidney Dis 2002;40:37–42.
3
Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition
Examination Survey-. Arthritis Rheum. 2011;63(10):-
Choi HK, Mount DB, Reginato AM, American College of Physicians, American Physiological Society. Pathogenesis of gout. Ann Intern Med.
2005;143(7):-
Enomoto, A. et al. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 2002;417,-
Richette P, Bardin T. Gout. Lancet 2010; 375:318–28.
7
Glantzounis GK, Tsimoyiannis EC, Kappas AM, et al. Uric acid and oxidative stress. Curr Pharm Des. 2005;11(32):-
Hediger, M. A. New view at C. Nature Med. 8, 445–446 (2002)
9
Roch-Ramel, F. & Guisan, B. News Physiol. Sci. 14, 80–84 (1999)
10
Keizman, D., et al. "Low-grade systemic inflammation in patients with amyotrophic lateral sclerosis." Acta Neurologica Scandinavica 119.6
(2009):-
Rentzos M, Nikolaou C, Anagnostouli M, Rombos A, Tsakanikas K, Economou M, et al. Serum uric acid and mul- tiple sclerosis.
ClinNeurolNeurosurg 2006; 108:-
Kim TS, Pae CU, Yoon SJ, Jang WY, Lee NJ, Kim JJ, et al. Decreased plasma antioxidants in patients with Alzheimer's disease. Int J Geriatr
Psychiatry 2006; 21:344–8.
13
Andreadou E, Nikolaou C, Gournaras F, Rentzos M, Boufidou F, Tsoutsou A, et al. Serum uric acid levels in pa- tients with Parkinson's
disease: their relationship to treatment and disease duration. ClinNeurolNeurosurg 2009; 111:724–8.
14
Auinger P, Kieburtz K, McDermott MP. The relationship between uric acid levels and Huntington's disease progression. MovDisord 2010;
25:224–8.
15
Alvarez-Lario B, Macarrón-Vicente J. Is there anything good in uric acid? QJM. 2011
16
Zhang W, Doherty M, Pascual E et al. EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the
Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2006;65:-
Schlesinger N, Norquist JM, Watson DJ. Serum Urate During Acute Gout. The Journal of Rheumatology. 2009;36(6):-
Sun SZ, Flickinger BD, Williamson-Hughes PS, Empie MW. Lack of association between dietary fructose and hyperuricemia risk in
adults.NutrMetab. 2010;7(1):16.
19
Alvarez-Lario B, Macarrón-Vicente J. Is there anything good in uric acid? QJM. 2011.
20
Campion EW, Glynn RJ, DeLabry LO.Asymptomatic hyper- uricemia.Risk and consequences in the Normative Aging Study.Am J Med 1987;
82:421–6.
21
Puig JG, de Miguel E, Castillo MC, Rocha AL, Martinez MA, Torres RJ. Asymptomatic hyperuricemia: impact of ultrasonography.
Nucleosides Nucleotides Nucleic Acids 2008;27:592–5.
22
Doherty M. New insights into the epidemiology of gout.Rheumatology (Oxford). 2009;48Suppl 2:ii2–ii8.
23
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature
2006;440:-
Eggebeen AT. Gout: an update. Am Fam Physician. 2007;76(6):-
Doherty M. New insights into the epidemiology of gout.Rheumatology (Oxford). 2009;48Suppl 2:ii2–ii8.
26
Eggebeen AT. Gout: an update. Am Fam Physician. 2007;76(6):-
Pascual E. Persistence of monosodium urate crystals and low-grade inflammation in the synovial fluid of patients with untreated gout.Arthritis
Rheum 1991; 34:141–5.
28
Chhana A, Callon KE, Pool B, et al. Monosodium urate monohydrate crystals inhibit osteoblast viability and function: implications for
development of bone erosion in gout. Ann. Rheum. Dis. 2011;70(9):-
Eggebeen AT. Gout: an update. Am Fam Physician. 2007;76(6):-
Pak CY, Moe OW, Sakhaee K, Peterson RD, Poindexter JR. Physicochemical metabolic characteristics for calcium oxal- ate stone formation in
patients with gouty diathesis. J Urol 2005; 173:-
Johnson RJ, Kivlighn SD, Kim YG, Suga S, Fogo AB. Reappraisal of the pathogenesis and consequences of hyper- uricemia in hypertension,
cardiovascular disease, and renal disease. Am J Kidney Dis 1999; 33:-
Alvarez-Lario B, Macarrón-Vicente J. Is there anything good in uric acid? QJM. 2011.
Kim SY, Guevara JP, Kim KM, Choi HK, Heitjan DF, Albert DA. Hyperuricemia and risk of stroke: a systematic review and meta-analysis.
Arthritis Rheum 2009; 61:-
Ekundayo OJ, Dell'Italia LJ, Sanders PW, et al. Association between hyperuricemia and incident heart failure among older adults: a propensitymatched study. Int. J. Cardiol. 2010;142(3):-
REFERENCES [ pg.
35
164 ]
Kim SY, Guevara JP, Kim KM, Choi HK, Heitjan DF, Albert DA. Hyperuricemia and coronary heart disease: a sys- tematic review and metaanalysis. Arthritis Care Res 2010; 62:-
Mazzali M, Kanbay M, Segal MS, Shafiu M, Jalal D, Feig D, et al. Uric acid and hypertension: cause or effect? CurrRheumatol Rep 2010;
12:-
Grayson PC, Kim SY, LaValley M, Choi HK. Hyperuricemia and incident hypertension: a systematic review and meta-analysis. Arthritis Care
Res. 2011;63(1):-
Feig DI, Soletsky B, Johnson RJ. Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a
randomized trial. JAMA. 2008;300(8):-
Glantzounis GK, Tsimoyiannis EC, Kappas AM, et al. Uric acid and oxidative stress. Curr Pharm Des. 2005;11(32):-
Doherty M. New insights into the epidemiology of gout.Rheumatology (Oxford). 2009;48Suppl 2:ii2–ii8.
41
Dao HH, Harun-Or-Rashid M, Sakamoto J. Body compos- ition and metabolic syndrome in patients with primary gout in Vietnam.
Rheumatology 2010; 49:-
Choi HK, Ford ES.Prevalence of the metabolic syndrome in individuals with hyperuricemia.Am J Med 2007; 120:442–7.
43
Choi HK, De Vera MA, Krishnan E. Gout and the risk of type 2 diabetes among men with a high cardiovascular risk profile. Rheumatology
(Oxford). 2008;47(10):-
Singh JA, Reddy SG, Kundukulam J. Risk factors for gout and prevention: a systematic review of the literature. CurrOpinRheumatol.2011:1.
45
Bierer DW, Quebbemann AJ.Effect of L-dopa on renal handling of uric acid.J PharmacolExpTher. 1982;223(1):55–59.
46
Scott JT. Drug-induced gout. Baillieres Clin Rheumatol. 1991 Apr;5(1):39-60.
47
Doherty M. New insights into the epidemiology of gout.Rheumatology (Oxford). 2009;48Suppl 2:ii2–ii8.
48
Doherty M. New insights into the epidemiology of gout.Rheumatology (Oxford). 2009;48Suppl 2:ii2–ii8.
49
Caspi D, Lubart E, Graff E, et al. The effect of mini-dose aspirin on renal function and uric acid handling in elderly patients.Arthritis Rheum.
2000;43(1):-
Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J
Med. 2004a;350(11):-
Choi HK, Curhan G. Beer, liquor, wine, and serum uric acid level: the Third National Health and Nutrition Examination Survey. Arthritis
Rheum 2004; 51:1023 – 1029.
52
Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Alcohol intake and risk of incident gout in men: a prospective study. Lancet.
2004b;-):-
Ibid.
54
Neogi, Tuhina, et al. "Alcohol quantity and type on risk of recurrent gout attacks: an internet-based case-crossover study." The American
journal of medicine 127.4 (2014):-
Puig JG, Fox IH. Ethanol-induced activation of adenine nucleotide turnover.Evidence for a role of acetate. J Clin Invest 1984; 74:-
Vandenberg MK, Moxley G, Breitbach SA, Roberts WN. Gout attacks in chronic alcoholics occur at lower serum urate levels than in
nonalcoholics. J Rheumatol 1994; 21:-
Gibson T, Rodgers AV, Simmonds HA, Toseland P. Beer drinking and its effect on uric acid. Br J Rheumatol 1984; 23:-
Choi JWJ, Ford ES, Gao X, Choi HK. Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and
Nutrition Examination Survey. Arthritis Rheum. 2008b;59(1):-
Sun SZ, Flickinger BD, Williamson-Hughes PS, Empie MW. Lack of association between dietary fructose and hyperuricemia risk in
adults.NutrMetab. 2010;7(1):16.
60
Ibid.
61
Jamnik J, Rehman S,Blanco Mejia S,etal.Fructose intake and risk ofgout and hyperuricemia: asystematic review and meta-analysis of
prospectivecohort studies.BMJOpen2016;6:e013191.doi:10.1136/bmjopen-
http://www.greenmedinfo.com/article/high-fructose-corn-syrup-and-fructose-consumption-increase-risk-factors
63
Schlesinger N, Norquist JM, Watson DJ. Serum Urate During Acute Gout. The Journal of Rheumatology. 2009;36(6):-
Zhang W, Doherty M, Pascual E et al. EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the
Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2006a;65:-
Kasper DL Braunwald DE et al. Harrison's Principles of Internal Medicine . 16th ed. New York , NY : McGraw-Hill Professional; 2005.
66
De Miguel E, Puig JG, Castillo C, et al. Diagnosis of gout in patients with asymptomatic hyperuricaemia: a pilot ultrasound study. Ann.
Rheum. Dis. 2011.
67
Zhang W, Doherty M, Bardin T, et al. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the
EULAR Standing Committee For International Clinical Studies Including Therapeutics (ESCISIT). Ann. Rheum. Dis. 2006b;65(10):-
Becker MA, Schumacher HR, Wortmann RL, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J
Med. 2005;353(23):-
FDA. FDA approves new drug for gout. FDA NEWS RELEASE. Sept. 14, 2010. Available at
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2010/ucm225810.htm
70
Sundy JS et al. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two
randomized controlled trials. JAMA. 2011 Aug 17;306(7):-
Ea HK et al. Pegloticase and chronic gout.JAMA. 2011 Nov 9;306(18):1979; author reply-
Larmon WA (1970) Surgical management of tophaceous gout. ClinOrthopRelat Res 71:56–69.
REFERENCES [ pg.
73
165 ]
Ford TC (1992) Surgical management of chronic tophaceous gout. A case report. J Am Podiatr Med Assoc 82(10):514–519.
Saey, Tina Hesman. “The Vast Virome.”Microbes,Ecosystems,Health. Science News, 18 Nov. 2016
75
Bianconi, Eva, et al. “An estimation of the number of cells in the human body.” Annals of Human Biology 40.6 (2013):-
Saey, Tina Hesman. “The Vast Virome.”Microbes,Ecosystems,Health. Science News, 18 Nov. 2016
77
Neu, Josef, and Jona Rushing. “Cesarean Versus Vaginal Delivery: Long Term Infant Outcomes and the Hygiene Hypothesis.” 38.2 : Web
Based. 28 Nov. 2016
78
“The Human Microbiome.” Utah.edu. (Web based) 19 Nov. 2016
79
Cho, Ilseung, and Martin J Blaser. “The Human Microbiome: At the Interface of Health and Disease.” Nature Reviews Genetics 13.4 (2012):-
Ramakrishna, BS. “Role of the Gut Microbiota in Human Nutrition and Metabolism.”Journal of gastroenterology and hepatology. 28. (2013):
9–17
81
“The Human Microbiome.” Utah.edu. (Web based)19Nov. 2016
82
Cho, Ilseung, and Martin J Blaser.“The Human Microbiome: At the Interface of Health and Disease.” Nature Reviews Genetics 13.4 (2012):-
Saey, Tina Hesman. “Body’s Bacteria Don’t Outnumber Human Cells so Much After All.” Microbiology, Physiology. Science News, Mar.
2016.
84
“Your Changing Microbiome.” Web Based. 19 Nov. 2016
85
Ursell, Luke K, et al. “Defining the Human Microbiome.” 70.Suppl 1 Web based. 19 Nov. 2016.
86
Saey, Tina Hesman. “The Vast Virome.” Microbes,Ecosystems,Health. Science News, 18 Nov. 2016
87
Sender, Ron, et al. “Revised Estimates for the Number of Human and Bacteria Cells in the Body.” New Results (2016):-
Bianconi, Eva, et al. “An estimation of the number of cells in the human body.” Annals of Human Biology 40.6 (2013):-
Saey, Tina Hesman. “The Vast Virome.” Microbes,Ecosystems,Health. Science News, 18 Nov. 2016.
90
Milliken, Grennan. ARE VIRUSES ALIVE? NEW EVIDENCE SAYS YES. Popular Science (Web Based) 2016.
91
Neu, Josef, and Jona Rushing. “Cesarean Versus Vaginal Delivery: Long Term Infant Outcomes and the Hygiene Hypothesis.” 38.2 : Web
Based. 28 Nov. 2016.
92
Peterson, Jane, et al. “The NIH Human Microbiome Project.” (2009):
93
Ibid.
94
“Exploring the role of gut bacteria in digestion.” (2010)
95
Ramakrishna, BS. “Role of the Gut Microbiota in Human Nutrition and Metabolism.” Journal of gastroenterology and hepatology. 28. (2013):
9–17.
96
Ibid.
97
Bäckhed, F, et al. “The Gut Microbiota as an Environmental Factor That Regulates Fat Storage.” Proceedings of the National Academy of
Sciences of the United States of America. 101.44 (2004):-
Carabotti, Marilia, et al. “The Gut-Brain Axis: Interactions Between Enteric Microbiota, Central and Enteric Nervous Systems.”Central and
Enteric Nervous Systems.” (2015)
99
Ibid.
100
Ramakrishna, BS. “Role of the Gut Microbiota in Human Nutrition and Metabolism.” Journal of gastroenterology and hepatology. 28. (2013):
9–17.
101
Ibid.
102
Belkaid, Yasmine, and Timothy Hand. “Role of the Microbiota in Immunity and Inflammation.” 157.1 (2014):
103
Kau, Andrew, et al. “Human Nutrition, the Gut Microbiome, and Immune System: Envisioning the Future.” Nature (2011):-
Neu, Josef, and Jona Rushing. “Cesarean Versus Vaginal Delivery: Long Term Infant Outcomes and the Hygiene Hypothesis.” 38.2 (Web
based)
105
Mueller, Noel T., et al. “The Infant Microbiome Development: Mom Matters.” 21.2 -
“Your Changing Microbiome.” Web Based. 19 Nov-
Dominguez-Bello, MG, et al. “Delivery Mode Shapes the Acquisition and Structure of the Initial Microbiota Across Multiple Body Habitats in
Newborns.” Proceedings of the National Academy of Sciences of the United States of America. 107.26 (2010):-
Ibid.
109
MacIntyre, David A., et al. “The Vaginal Microbiome During Pregnancy and the Postpartum Period in a European Population.” -
Ibid.
111
Filippo, De, et al. “Impact of Diet in Shaping Gut Microbiota Revealed by a Comparative Study in Children from Europe and Rural Africa.”
Proceedings of the National Academy of Sciences of the United States of America. 107.33 (2010):-
Conlon, Michael A., and Anthony R. Bird. “The Impact of Diet and Lifestyle on Gut Microbiota and Human Health.” 7.1 -
Guo Z, Zhang J, Wang Z, et al. Intestinal microbiota distinguish gout patients from healthy humans. Sci Rep. 2016; 6:20602.
doi:10.1038/srep-
Z. Guo et al (2016) Intestinal Microbiota Distinguish Gout Patients from Healthy Humans. Nature scientific reports
115
Guo, Zhuang, et al. "Intestinal microbiota distinguish gout patients from healthy humans." Scientific reports 6 (2016):-
Shao, Tiejuan, et al. "Combined signature of the fecal microbiome and metabolome in patients with gout." Frontiers in microbiology 8 (2017):
268.
74
REFERENCES [ pg.
117
166 ]
Guo Z, Zhang J, Wang Z, et al. Intestinal microbiota distinguish gout patients from healthy humans. Sci Rep. 2016; 6:20602.
doi:10.1038/srep-
Shao, Tiejuan, et al. "Combined signature of the fecal microbiome and metabolome in patients with gout." Frontiers in microbiology 8 (2017):
268.
119
Z. Guo et al (2016) Intestinal Microbiota Distinguish Gout Patients from Healthy Humans. Nature scientific reports
120
Guo, Zhuang, et al. "Intestinal microbiota distinguish gout patients from healthy humans." Scientific reports 6 (2016):-
Hosomi, A., Nakanishi, T., Fujita, T. & Tamai, I. (2012) Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.
PloS One 7, e-
Guo, Zhuang, et al. "Intestinal microbiota distinguish gout patients from healthy humans." Scientific reports 6 (2016):-
Wei, B. et al. Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by an inflammatory bowel disease
marker antibody. Infect Immun 69,- (2001).
124
Guo, Zhuang, et al. "Intestinal microbiota distinguish gout patients from healthy humans." Scientific reports 6 (2016):-
Wei, B. et al. Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by an inflammatory bowel disease
marker antibody. Infect Immun 69,- (2001).
126
Wei, B. et al. Molecular cloning of a Bacteroides caccae TonB-linked outer membrane protein identified by an inflammatory bowel disease
marker antibody. Infect Immun 69,- (2001).
127
Guo, Zhuang, et al. "Intestinal microbiota distinguish gout patients from healthy humans." Scientific reports 6 (2016):-
https://www.harvardmagazine.com/2019/05/inflammation-disease-diet (accessed May-
Ibid.
130
Journal of Nutritional Biochemistry August 2013: 24(8);-
Journal of Nutritional Biochemistry August 2013: 24(8);-
http://ilsi.org/europe/wp-content/uploads/sites/3/2016/05/Prebiotics-Probiotics.pdf
133
Ibid.
134
Wong, Victor W., et al. "From germ theory to germ therapy: skin microbiota, chronic wounds, and probiotics." Plastic and reconstructive
surgery 132.5 (2013): 854e-861e.
135
Peral, Maria C., Miguel A. Huaman Martinez, and Juan C. Valdez. "Bacteriotherapy with Lactobacillus plantarum in burns." International
wound journal 6.1 (2009):-
Prince, Tessa, Andrew J. McBain, and Catherine A. O'Neill. "Lactobacillus reuteri protects epidermal keratinocytes from Staphylococcus
aureus induced cell death by competitive exclusion." Applied and environmental microbiology (2012): AEM-
Friedrich, Adrián D., et al. "Message in a bottle: dialog between intestine and skin modulated by probiotics." International journal of
molecular sciences 18.6 (2017):-
Iemoli, Enrico, et al. "Probiotics reduce gut microbial translocation and improve adult atopic dermatitis." Journal of clinical gastroenterology
46 (2012): S33-S40.
139
Al-Ghazzewi, F. H., and R. F. Tester. "Impact of prebiotics and probiotics on skin health." Beneficial microbes 5.2 (2014):-
Petschow, Bryon, et al. "Probiotics, prebiotics, and the host microbiome: the science of translation." Annals of the New York Academy of
Sciences 1306.1 (2013): 1-17.
141
Bouhnik, Yoram, et al. "The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind,
randomized, placebo-controlled, parallel-group, dose-response relation study." The American journal of clinical nutrition 80.6 (2004):-
Hughes, Christine, et al. "Galactooligosaccharide supplementation reduces stress-induced gastrointestinal dysfunction and days of cold or flu:
a randomized, double-blind, controlled trial in healthy university students–." The American journal of clinical nutrition 93.6 (2011):-
http://www.glycemic.com/GlycemicIndex-LoadDefined.htm
144
Nierenberg C. Probiotics Hold Promise for 4 Skin Conditions. Live Science Website.
http://www.livescience.com/46502-probiotics-hold-promise-skin-conditions.html.
Published June24,-
Goldin B, Gorbach S. Clinical Indications for Probiotics: An Overview. Clinical Infectious Diseases. 2008;46(s2):S96-S100.
Doi10.1086/-
Heid M. Craving Junk Food? Get Bacteria Prevention. http://www.prevention.com/food/healthy-eating-tips/gut-bacteria-and-cravings.Updated
September 11,-
Alcock J, Maley C, Aktipis C. Is eating behavior manipulated by gastrointestinal microbiota? Evolutionary pressures and potential
mechanisms. BioEssays. 2014;36(10):940-949. Doi10.1002/bies-
Russo J. List of Good Bacteria. Livestrong Website. http://www.livestrong.com/article/26093-list-good-bacteria/. Updated August 13,-
Salazar N, Dewulf E, Neyrinck A et al. Inulin-type fructans modulate intestinal Bifidobacterium species populations and decreases fecal shortchain fatty acids in obese women. Clinical Nutrition. 2015;34(3):501-507. Doi:10.1016/j.cinu-
Courage K. Fiber-Famished Gut Microbes Linked to Poor Health. Scientific American. https//www.scientifcamerican.com/article/fiberfamished-gut-microbes-linked-to-poor-health1/. Published March 23,-
Aragon G, Graham DB, Borum M, Doman DB. Probiotic Therapy for Iritable Bowel Syndrome. Gastroenterol Hepatol (NY). 2010 Jan;
6(1):39-44.
REFERENCES [ pg.
152
167 ]
MacDonald F. Your Gut Bacteria Can Reveal Which Diet Will Actually Work For You. Science Alert. http://sciencealert.com/your-gutbacteria-determines-which-diets-will-actually-make-you-lose-weight. Published September 11,-
Oriach C, Roberston R, Stanton C, Cryan J, Dinan T. Food for thought The role of nutrition in microbiota-gut-brain axis-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC-/#B8
155
Pierini C. Vitamin Research News. Jan-): 1-4.
156
Coppo R, Amore A, Roccatello D. Dietary antigens and primary IgA nephropathy. J Am Soc Nephrol. 1992;2(10 suppl):S173–S180
157
Stone M. NIH Builds Substantial Human Microbiome Project. Microbe Magazine. 2009, 4(10):451 - 456
158
Ackerman J. The Ultimate Social Network. SciAm. 2012: 306(6): 36 – 43 doi: 10.1038/scientificamerican-
Neu. J. Rushing J. Cesarean versus Vaginal Delivery: Long-term Infant Outcomes and the Hygiene Hypothesis. Clinics in Preinatalogy
2011;38(2):321-331 doi:10.1016/j.clp-
Carpenter S. The Gut Feeling. American Psychological Association. 2012;43(8):50
161
Justin Sonnenburg E. Gut feelings – the “Second Brain” in our Gastrointestinal Systems [Exerpt]. Scientific American website.
https://www.scientificamerican.com/article/gut-feelings-the-second-brain-in-our-gastrointestinal-systems-exerpt/.
162
Dethlefson L, Huse S, Sogin M, Relman D. The Pervasive Efects of an Antibiotic on Human Gut Microbiota, as Revealed by Deep 16S rRNA
Sequencing. PLoS Biology. 2008;6(11):e280. Doi:10.1371/journal.pbio-
Phillips I. Does the use of antibiotics in food animals pose a risk to human health? A critical review of published data. Journal of
Antimicrobial Chemotherapy. 2003;-. Doi 10.1093/jac/dkg482.
164
Abou-Donia MB, El-Masry EM, Abdel-Rahman AA, Mclendron RE, Schiffman SS. Splenda alters gut microbiota and increases intestinal pglycoprotein and cytochrome p-450 in rats. J Toxicol Environ Health A. 2008;71(21):1415-29. Doi: 10.1080/-
https://plan.core-apps.com/acsboston18/abstract/dc6b8b7c-001f-49b3-82c2-3feca7a7a39c
166
Mayta-Apaza, Alba C., et al. "Impact of tart cherries polyphenols on the human gut microbiota and phenolic metabolites in vitro and in vivo."
The Journal of Nutritional Biochemistry (2018).
167
Franck Carbonero, PhD, assistant professor in the Department of Food Science at the University of Arkansas.
168
Moon D-O, Kim M-O, Choi YH, Park Y-M, Kim G-Y.Curcumin attenuates inflammatory response in IL-1β-induced human synovial
fibroblasts and collagen-induced arthritis in mouse model. International Immunopharmacology. 2010;10(5):-
Belcaro G, Cesarone MR, Dugall M, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended
administration in osteoarthritis patients. Altern Med Rev. 2010;15(4):-
Wann AK, Mistry J, Blain EJ, Michael-Titus AT, Knight MM. Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1βmediated cartilage degradation. Arthritis Res. Ther. 2010;12(6):R207.
171
Choi HK. A prescription for lifestyle change in patients with hyperuricemia and gout.CurrOpinRheumatol. 2010;22(2):-
Shakibaei M, Csaki C, Nebrichi S, Mobasheri A. Resveratrol suppresses interleukin-1β-induced inflammatory signaling and apoptosis in
human articular chondrocytes: Potential for use as a novel nutraceutical for the treatment of osteoarthritis. Biochem.Pharmacol.
2008;76(11):-
Tate GA, Mandell BF, Karmali RA, et al. Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with
gamma-linolenic acid and eicosapentaenoic acid. Arthritis Rheum. 1988;31(12):-
Feigelson P. The inhibition of xanthine oxidase in vitro by trace amounts of I-ascorbic acid. J BiolChem 1952;197:-
Juraschek SP, Miller ER III, Gelber AC. Effect of oral vitamin C supplementation on serum uric acid: A meta-analysis of randomized
controlled trials. Arthritis Care Res. 2011;63(9):-
Huang H-Y, Appel LJ, Choi MJ, et al. The effects of vitamin C supplementation on serum concentrations of uric acid: Results of a randomized
controlled trial. Arthritis Rheum. 2005;52(6):-
Bates CJ, Walmsley CM, Prentice A, Finch S. Does vitamin C reduce blood pressure?Results of a large study of people aged 65 or older. J.
Hypertens. 1998 Jul;16(7):925.
178
Block G, Jensen CD, Norkus EP, Hudes M, Crawford PB. Vitamin C in plasma is inversely related to blood pressure and change in blood
pressure during the previous year in young Black and White women. Nutr J 2008;7:35.
179
http://www.sciencedirect.com/science/article/pii/S-
http://onlinelibrary.wiley.com/doi/10.1111/j-.x/full
181
http://atvb.ahajournals.org/content/31/12/3011.short
182
http://www.greenmedinfo.com/article/higher-dietary-intakes-selenium-vitamin-c-vitamin-e-carotene-and-cryptoxanthin
183
http://www.nejm.org/doi/pdf/10.1056/NEJM-
http://www.greenmedinfo.com/article/higher-intake-vitamin-c-might-have-protective-effect-against-lung-cancer
185
http://jnci.oxfordjournals.org/content/98/4/245.short
186
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC-/
187
Padayatty, Sebastian J., et al. "Vitamin C as an antioxidant: evaluation of its role in disease prevention." Journal of the American College of
Nutrition 22.1 (2003):-
Cook, James D., and Elaine R. Monsen. "Vitamin C, the common cold, and iron absorption." The American journal of clinical nutrition 30.2
(1977):-
Fain, O. "[Vitamin C deficiency]." La Revue de medecine interne/fondee... par la Societe nationale francaise de medecine interne 25.12
(2004): 872-880.
REFERENCES [ pg.
190
168 ]
Karaoz, Erdal, et al. "Protective role of melatonin and a combination of vitamin C and vitamin E on lung toxicity induced by chlorpyrifosethyl in rats." Experimental and Toxicologic Pathology 54.2 (2002):-
Allard, Johane P., et al. "Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects." Aids 12.13
(1998):-
Blau LW. Cherry diet control for gout and arthritis. Tex Rep BiolMed . 1950;8(3):-
Jacob RA, Spinozzi GM, Simon VA, et al. Consumption of cherries lowers plasma urate in healthy women. J Nutr. 2003;133(6):-
Fam AG. Gout: excess calories, purines, and alcohol intake and beyond. Response to a urate-lowering diet. J Rheumatol . 2005
May;32(5):-
Jacob RA, Spinozzi GM, Simon VA, et al. Consumption of cherries lowers plasma urate in healthy women. J Nutr. 2003;133(6):-
Jancin B. Cherry Juice Flowing in Gout Treatment Pipeline.Family Practice News-
Hossain, Md Farid, Shaheen Akhtar, and Mustafa Anwar. "Nutritional value and medicinal benefits of pineapple." International Journal of
Nutrition and Food Sciences 4.1 (2015):-
Azmi, S. M. N., P. Jamal, and A. Amid. "Xanthine oxidase inhibitory activity from potential Malaysian medicinal plant as remedies for gout."
International Food Research Journal 19.1 (2012): 159.
199
Salazar-Martinez E, Willett WC, Ascherio A, Manson JE, Leitz- mann MF, Stampfer MJ, et al. Coffee consumption and risk for type 2
diabetes mellitus. Ann Intern Med 2004;140:1–8.
200
Choi HK, Curhan G. Coffee consumption and risk of incident gout in women: the Nurses' Health Study. American Journal of Clinical
Nutrition. 2010;92(4):-
Choi HK, Willett W, Curhan G. Coffee consumption and risk of incident gout in men: a prospective study. Arthritis Rheum. 2007;56(6):-
Kela U, Vijayvargiya R, Trivedi CP. Inhibitory effects of methyl-xanthines on the activity of xanthine oxidase. Life Sci 1980;27:-
Mascitelli L, Goldstein MR. Does inhibition of iron absorption by coffee reduce the risk of gout? Int. J. Clin. Pract. 2011;65(6):713.
204
Farah A et al. Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr. 2008 Dec;138(12):-
Romero-Gonzalez RR et al. Salting-out gradients in centrifugal partition chromatography for the isolation of chlorogenic acids from green
coffee beans. J Chromatogr A. 2009 May 8;1216(19):4245-51. Epub-
Ahmad, Muhammed Saeed, and Nessar Ahmed. "Antiglycation properties of aged garlic extract: possible role in prevention of diabetic
complications." The Journal of nutrition 136.3 (2006): 796S-799S.
207
Okada, Youji, et al. "Kinetic and mechanistic studies of allicin as an antioxidant." Organic &biomolecular chemistry 4.22 (2006):-
Liu, Cheng-Tzu, Lee-Yan Sheen, and Chong-KueiLii. "Does garlic have a role as an antidiabetic agent?." Molecular nutrition & food research
51.11 (2007):-
Coppi, Alida, et al. "Antimalarial activity of allicin, a biologically active compound from garlic cloves." Antimicrobial Agents and
chemotherapy 50.5 (2006):-
Ledezma, E., and R. Apitz-Castro. "Ajoene the main active compound of garlic (Allium sativum): a new antifungal agent."
Revistaiberoamericana de micologia 23.2 (2006):-
Sun SZ, Flickinger BD, Williamson-Hughes PS, Empie MW. Lack of association between dietary fructose and hyperuricemia risk in
adults.NutrMetab. 2010;7(1):16.
212
Lyu L-C, Hsu C-Y, Yeh C-Y, et al. A case-control study of the association of diet and obesity with gout in Taiwan.Am J ClinNutr.
2003;78(4):-
Koguchi T, Koguchi H, Nakajima H, Takano S, Yamamoto Y, Innami S, Maekawa A, Tadokoro T: Dietary fiber suppresses elevation of uric
acid and urea nitrogen concentrations in serum of rats with renal dysfunction induced by dietary adenine. Int J VitamNutr Res 2004, 74(4):-
Streppel MT, Arends LR, van t Veer P, Grobbee DE, Geleijnse JM. Dietary fiber and blood pressure: a meta-analysis of randomized placebocontrolled trials. Arch Intern Med 2005 Jan.;165(2):-
Whelton SP, Hyre AD, Pedersen B, Yi Y, Whelton PK, He J. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized,
controlled clinical trials. J. Hypertens. 2005 Mar.;23(3):-
Brown L, Rosner B, Willett WW, Sacks FM. Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J ClinNutr 1999 Jan.;69(1):-
Whitehouse, M. W., and D. E. Butters. "Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some
herbal/animal products." Inflammopharmacology 11.4-6 (2003): 453-464. (https://link.springer.com/article/10.1163/-
Soundararajan S and Daunter B: Ajvine: Pilot biomedical study for pain relief in rheumatic pain. School of Medicine,The University of
Queensland, Brisbane, Queensland, Australia,-
Venkat S, Soundararajan S, Daunter B and Madhusudhan S. Use of Ayurvedic medicine in the treatment of rheumatic illness. Department of
Orthopaedics, Kovai Medical Center and Hospitals, Coimbatore, India,-
Abhishek, Abhishek, Ana M. Valdes, and Michael Doherty. "Low omega-3 fatty acid levels associate with frequent gout attacks: a case
control study." Annals of the rheumatic diseases 75.4 (2016):-
Madhavi, Doddabele, Daniel Kagan, and Venkatesh Rao. "A pilot study to evaluate the antihypertensive effect of a celery extract in mild to
moderate hypertensive patients." Age 57.10 (2013).
REFERENCES [ pg.
222
169 ]
Powanda, Michael C., Michael W. Whitehouse, and K. D. Rainsford. "Celery seed and related extracts with antiarthritic, antiulcer, and
antimicrobial activities." Novel Natural Products: Therapeutic Effects in Pain, Arthritis and Gastro-intestinal Diseases. Springer, Basel,-
Ibid.
224
Ibid.
225
Zurier, Robert B., et al. "Gamma-linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial." Arthritis &
Rheumatism 39.11 (1996):-
Tate, G. U. I. L. L. E. R. M. O., et al. "Suppression of acute and chronic inflammation by dietary gamma linolenic acid." J Rheumatol 16.6
(1989):-
Kast, Richard E. "Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis
factor-alpha." International immunopharmacology 1.12 (2001):-
Belch, Jill JF, and Alexander Hill. "Evening primrose oil and borage oil in rheumatologic conditions." The American journal of clinical
nutrition 71.1 (2000): 352s-356s.
229
Barre, D. Edward. "Potential of evening primrose, borage, black currant, and fungal oils in human health." Annals of nutrition and metabolism
45.2 (2001):-
Watson, J., et al. "Cytokine and prostaglandin production by monocytes of volunteers and rheumatoid arthritis patients treated with dietary
supplements of blackcurrant seed oil." Rheumatology 32.12 (1993):-
Brzeski, M., R. Madhok, and H. A. Capell. "Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal antiinflammatory drugs." Rheumatology 30.5 (1991):-
Zurier, Robert B., et al. "Gamma-linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial." Arthritis &
Rheumatism 39.11 (1996):-
Qin, Xianhui, et al. "Effect of folic acid supplementation on risk of new-onset diabetes in adults with hypertension in China: Findings from the
China Stroke Primary Prevention Trial (CSPPT)." Journal of diabetes 8.2 (2016):-
http://umm.edu/Health/Medical/AltMed/Supplement/Vitamin-B9-Folic-acid
235
Moat, Stuart J., et al. "Folate, homocysteine, endothelial function and cardiovascular disease." The Journal of nutritional biochemistry 15.2
(2004):-
Van Guelpen B, Hultdin J, Johansson I, et al. Plasma folate and totlal homocysteine levels are associated with the risk of myocardial
infarction, independently of each other and of renal function. J Intern Med. 2009;266(2):-
udchada P, Saokaew S, Sridetch S, et al. Effects of folic acid supplementation on plasma total homocysteine levels and glycemic control in
patients with type 2 diabetes: a systematic review and meta-analysis. Diabetes Res ClinPract. 2012;98(1):-
Lyu L-C, Hsu C-Y, Yeh C-Y, et al. A case-control study of the association of diet and obesity with gout in Taiwan.Am J ClinNutr.
2003;78(4):-
Kong LD, Cai Y et al. Inhibition of xanthine oxidase by some Chinese medicinal plants used to treat gout. J Ethnopharmacol . 2000 Nov;73(12):-
Ibid.
241
https://www.ncbi.nlm.nih.gov/pubmed/-
https://www.ncbi.nlm.nih.gov/pubmed/-
https://www.ncbi.nlm.nih.gov/pubmed/-
https://www.phcog.com/article.asp?issn=-;year=2011;volume=7;issue=28;spage=320;epage=324;aulast=Hudaib
245
Chen L, Yin H, Lan Z, et al. Anti-hyperuricemic and nephroprotective effects of Smilax china L. J Ethnopharmacol. 2011;135(2):-
Yan H, Ma Y, Liu M, Zhou L. The Dual Actions of PaederiascandensExtract as a Hypouricemic Agent: Xanthine Oxidase Inhibitory Activity
and Uricosuric Effect. Planta Med. 2008;74(11):-
Motamarri S, Karthikeyan M, Kannan M, Rajasekar S. Terminalia belerica Roxb.—A phytopharmacological review. Int J Res
Pharma.2012;3:-
Kumar V, Ajeesh R, Vidyasagaran K, Chourasia S. Evaluation of pulp content and physical characters of Thriphala in Western Ghats, India.
Environment and Ecology. 2014;33(4):-
Motamarri S, Karthikeyan M, Kannan M, Rajasekar S. Terminalia belerica Roxb.—A phytopharmacological review. Int J Res
Pharma.2012;3:-
Usharani P, Nutalapati C, Pokuri VK, Kumar CU, Taduri G. A randomized, double-blind, placebo-, and positive-controlled clinical pilot study
to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with
hyperuricemia. Clinical pharmacology: advances and applications. 2016;8:-
Cock IE. The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae). Inflammopharmacol.Oct
2015;23(5):-
Usharani P, Nutalapati C, Pokuri VK, Kumar CU, Taduri G. A randomized, double-blind, placebo-, and positive-controlled clinical pilot study
to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with
hyperuricemia. Clinical pharmacology: advances and applications. 2016;8:-
J Ethnopharmacol. 2015 Sep 3. Epub 2015 Sep 3. PMID:-
Liu, Hung-Wen, et al. "Dietary (−)-epigallocatechin-3-gallate supplementation counteracts aging-associated skeletal muscle insulin resistance
and fatty liver in senescence-accelerated mouse." Journal of agricultural and food chemistry 63.38 (2015):-.
REFERENCES [ pg.
170 ]
Liu, Hung-Wen, et al. "Dietary (−)-epigallocatechin-3-gallate supplementation counteracts aging-associated skeletal muscle insulin resistance
and fatty liver in senescence-accelerated mouse." Journal of agricultural and food chemistry 63.38 (2015):-
Silva, Kamila C., et al. "Green Tea Is Neuroprotective in Diabetic RetinopathyGTNeuroprotection in the Diabetic Retina." Investigative
Ophthalmology & Visual Science 54.2 (2013):-
Oh, Jungbae, et al. "Selected tea and tea pomace extracts inhibit intestinal α-glucosidase activity in vitro and postprandial hyperglycemia in
vivo." International journal of molecular sciences 16.4 (2015):-
Uchiyama, Yumiko, Takuji Suzuki, and Kazuki Mochizuki. "Dietary supplementation with a low dose of (−)-epigallocatechin-3-gallate
reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats." Journal of nutritional science and
vitaminology 59.6 (2013):-
Brown, A. Louise, et al. "Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and
associated metabolic risk factors: randomized controlled trial." British journal of nutrition 101.06 (2009):-
Brown, A. Louise, et al. "Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and
associated metabolic risk factors: randomized controlled trial." British journal of nutrition 101.06 (2009):-
Takahashi M, Miyashita M, Suzuki K, Bae SR, Kim HK, Wakisaka T, . . . Yasunaga K. Acute ingestion of catechin-rich green tea improves
postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women. The British journal of nutrition. Nov 14
2014;112(9):-
Pauff JM, Hille R. Inhibition Studies of Bovine Xanthine Oxidase by Luteolin, Silibinin, Quercetin, and Curcumin. J. Nat. Prod.
2009;72(4):-
Lin C-M, Chen C-S, Chen C-T, Liang Y-C, Lin J-K.Molecular modeling of flavonoids that inhibits xanthine oxidase.BiochemBiophys Res
Commun. 2002;294(1):-
Li Y et al. Virtual and In vitro bioassay screening of phytochemical inhibitors from flavonoids and isoflavones against Xanthine oxidase and
Cyclooxygenase-2 for gout treatment.ChemBiol Drug Des.2011 Oct 3.doi: 10.1111/j-.x.
265
Flemmig J et al. Oleaeuropaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine
oxidase. Phytomedicine. 2011 May 15;18(7):561-6. Epub-
Mo S-F, Zhou F, Lv Y-Z, et al. Hypouricemic action of selected flavonoids in mice: structure-activity relationships. Biol. Pharm. Bull.
2007;30(8):-
Hu QH, Wang C, Li JM, Zhang DM, Kong LD. Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced
by fructose intake: renal organic ion transporter involvement. AJP: Renal Physiology. 2009;297(4):F1080–F-
Wang Y, Zhu JX et al. Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine
dehydrogenase/oxidase activities in oxonate-treated mice. Basic ClinPharmacolToxicol. 2004 May;94(5):-
Wang, Wei, et al. "In vitro antioxidant and antimicrobial activity of extracts from Morus alba L. leaves, stems and fruits." The American
journal of Chinese medicine 40.02 (2012):-
Wang, Cai-Ping, et al. "Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice." Planta medica 77.08
(2011):-
Chu, Qingcui, et al. "Study on capillary electrophoresis–amperometric detection profiles of different parts of Morus alba L." Journal of
Chromatography A 1116.1-2 (2006):-
Choi, Sang Won, et al. "Analysis of functional constituents in mulberry (Morus alba L.) twigs by different cultivars, producing areas, and heat
processings." Preventive nutrition and food science 18.4 (2013): 256.
273
Choi, Sang Won, et al. "Analysis of functional constituents in mulberry (Morus alba L.) twigs by different cultivars, producing areas, and heat
processings." Preventive nutrition and food science 18.4 (2013): 256.
274
Kikuchi, Takashi, et al. "Albanol A from the root bark of Morus alba L. induces apoptotic cell death in HL60 human leukemia cell line."
Chemical and Pharmaceutical Bulletin 58.4 (2010):-
Ahmad, Aftab, et al. "Antiulcer and antioxidant activities of a new steroid from Morus alba." Life sciences 92.3 (2013):-
Chung, Kyung-Ook, et al. "In-vitro and in-vivo anti-inflammatory effect of oxyresveratrol from Morus alba L." Journal of Pharmacy and
Pharmacology 55.12 (2003):-
Chen, Yi-Ching, et al. "Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration
involving MEK/ERK signaling." BMC complementary and alternative medicine 13.1 (2013): 45.
278
Chen, Shang-Ke, et al. "Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor." Bioorganic & medicinal chemistry letters
22.9 (2012):-
Lim, Hyun Hwa, et al. "Combined treatment of mulberry leaf and fruit extract ameliorates obesity-related inflammation and oxidative stress in
high fat diet-induced obese mice." Journal of medicinal food 16.8 (2013):-
Eo, Hyun Ji, et al. "Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark." BMC complementary and alternative
medicine 14.1 (2014): 200.
281
Da Hye Kwon, Ji Min Cheon, et al. "The immunomodulatory activity of mori folium, the leaf of Morus alba L., in raw 264.7 macrophages in
vitro." Journal of cancer prevention 21.3 (2016): 144.
282
Kim, Seon Beom, et al. "Macrophage activating activity of pyrrole alkaloids from Morus alba fruits." Journal of ethnopharmacology 145.1
(2013):-
Carrizzo, Albino, et al. "Morus alba extract modulates blood pressure homeostasis through eNOS signaling." Molecular nutrition & food
research 60.10 (2016):-
REFERENCES [ pg.
284
171 ]
Lee, Yun Jung, et al. "Hypotensive, hypolipidemic, and vascular protective effects of Morus alba L. in rats fed an atherogenic diet." The
American journal of Chinese medicine 39.01 (2011):-
Chan, Eric Wei-Chiang, L. Y. E. Phui-Yan, and W. O. N. G. Siu-Kuin. "Phytochemistry, pharmacology, and clinical trials of Morus alba."
Chinese journal of natural medicines 14.1 (2016):-
Enkhmaa, Byambaa, et al. "Mulberry (Morus alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate
atherosclerotic lesion development in LDL receptor-deficient mice." The Journal of nutrition 135.4 (2005):-
Chan, Eric Wei-Chiang, L. Y. E. Phui-Yan, and W. O. N. G. Siu-Kuin. "Phytochemistry, pharmacology, and clinical trials of Morus alba."
Chinese journal of natural medicines 14.1 (2016):-
Ibid
289
Naowaboot, Jarinyaporn, et al. "Mulberry leaf extract stimulates glucose uptake and GLUT4 translocation in rat adipocytes." The American
journal of Chinese medicine 40.01 (2012):-
Katsube, Takuya, et al. "Effect of flavonol glycoside in mulberry (Morus alba L.) leaf on glucose metabolism and oxidative stress in liver in
diet-induced obese mice." Journal of the Science of Food and Agriculture 90.14 (2010):-
El-Sayyad, H. I. H., et al. "Protective effects of Morus alba leaves extract on ocular functions of pups from diabetic and hypercholesterolemic
mother rats." International journal of biological sciences 7.6 (2011): 715.
292
Eo, Hyun Ji, et al. "Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark." BMC complementary and alternative
medicine 14.1 (2014): 200.
293
Chen, Hengwen, et al. "Extraction, purification and anti-fatigue activity of γ-aminobutyric acid from mulberry (Morus alba L.) leaves."
Scientific reports 6 (2016):-
Chan, Eric Wei-Chiang, L. Y. E. Phui-Yan, and W. O. N. G. Siu-Kuin. "Phytochemistry, pharmacology, and clinical trials of Morus alba."
Chinese journal of natural medicines 14.1 (2016):-
Kim, Hyo Geun, and Myung Sook Oh. "Memory-enhancing effect of Mori Fructus via induction of nerve growth factor." British Journal of
Nutrition 110.1 (2013):-
Kaewkaen, Pratchaya, et al. "Mulberry fruit extract protects against memory impairment and hippocampal damage in animal model of vascular
dementia." Evidence-Based Complementary and Alternative Medicine 2012 (2012).
297
Kim, Hyun Jung, et al. "HPLC-based activity profiling–discovery of sanggenons as GABAA receptor modulators in the traditional Chinese
drug sang bai pi (Morus alba root bark)." Planta medica 78.05 (2012):-
Yadav, Adhikrao V., and Vandana S. Nade. "Anti-dopaminergic effect of the methanolic extract of Morus alba L. leaves." Indian journal of
pharmacology 40.5 (2008): 221.
299
Ibid.
300
Lim, Dong Wook, et al. "Antidepressant-like effects of sanggenon G, isolated from the root bark of Morus alba, in rats: involvement of the
serotonergic system." Biological and Pharmaceutical Bulletin (2015): b-
Sattayasai, Jintana, Siriporn Tiamkao, and Prapawadee Puapairoj. "Biphasic effects of Morus alba leaves green tea extract on mice in chronic
forced swimming model." Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of
Natural Product Derivatives 22.4 (2008):-
Nade, Vandana S., et al. "Adaptogenic effect of Morus alba on chronic footshock-induced stress in rats." Indian journal of pharmacology 41.6
(2009): 246.
303
Chan, Eric Wei-Chiang, L. Y. E. Phui-Yan, and W. O. N. G. Siu-Kuin. "Phytochemistry, pharmacology, and clinical trials of Morus alba."
Chinese journal of natural medicines 14.1 (2016):-
De Oliveira, Alisson Macário, et al. "Evaluation of toxicity and antimicrobial activity of an ethanolic extract from leaves of Morus alba
L.(Moraceae)." Evidence-Based Complementary and Alternative Medicine 2015 (2015).
305
Park, K. M., et al. "Kuwanon G: an antibacterial agent from the root bark of Morus alba against oral pathogens." Journal of
ethnopharmacology 84.2-3 (2003):-
Lee, Jinmi, et al. "Regulation of obesity and lipid disorders by herbal extracts from Morus alba, Melissa officinalis, and Artemisia capillaris in
high-fat diet-induced obese mice." Journal of ethnopharmacology 115.2 (2008):-
Ann, Ji-Young, Hyeyoon Eo, and Yunsook Lim. "Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis,
and oxidative stress in high-fat diet-fed mice." Genes & nutrition 10.6 (2015): 46.
308
Yimam, Mesfin, et al. "Appetite suppression and antiobesity effect of a botanical composition composed of Morus alba, Yerba mate, and
Magnolia officinalis." Journal of obesity 2016 (2016).
309
Reiterer G, Toborek M, et al. Quercetin protects against linoleic acid-induced porcine endothelial cell dysfunction. J Nutr. 2004
Apr;134(4):-
Kuhlman DR, Schaefer CA, et al. Quercetin-induced induction of the NO/cGMP pathway depends on Ca2+-activated K+ channel-induced
hyperpolarization-mediated Ca2+-entry into cultured human endothelial cells. Planta Med. 2005 Jun;71(6):-
Machha A, Mustafa MR. Chronic treatment with flavonoids prevents endothelial dysfunction in spontaneously hypertensive rat aorta. J
CardiovascPharmacol. 2005 Jul;46(1):-
https://www.researchgate.net/profile/Samir_Samman/publication/-_FlavonoidsChemistry_metabolism_cardioprotective_effects_and_dietary_sources/links/0c-bccc0b-.pdf
313
https://www.researchgate.net/profile/Samir_Samman/publication/-_FlavonoidsChemistry_metabolism_cardioprotective_effects_and_dietary_sources/links/0c-bccc0b-.pdf
REFERENCES [ pg.
314
172 ]
Chung, Hoon; Dai, Tianhong; Sharma, Sulbha K.; Huang, Ying-Ying; Carroll, James D.; Hamblin, Michael R. (2011). "The Nuts and Bolts of
Low-level Laser (Light) Therapy". Annals of Biomedical Engineering. 40 (2):-
Ibid
316
Brosseau, L.; Welch, V.; Wells, G. A.; de Bie, R.; Gam, A.; Harman, K.; Morin, M.; Shea, B.; Tugwell, P. (2005). "Low level laser therapy
(Classes I, II and III) for treating rheumatoid arthritis". Cochrane Database of Systematic Reviews (4): CD-
Jamtvedt, G.; Dahm, K. T.; Christie, A.; Moe, R. H.; Haavardsholm, E.; Holm, I.; Hagen, K. B. (2007). "Physical Therapy Interventions for
Patients with Osteoarthritis of the Knee: an Overview of Systematic Reviews". Physical Therapy. 88 (1):-
Bjordal, JM; Couppé, C; Chow, RT; Tunér, J; Ljunggren, EA (2003). "A systematic review of low level laser therapy with location-specific
doses for pain from chronic joint disorders". The Australian Journal of Physiotherapy. 49 (2):-
Chow, R.; Johnson, M.; Lopes-Martins, R.; Bjordal, J. (Nov 2009). "Efficacy of low-level laser therapy in the management of neck pain: a
systematic review and meta-analysis of randomised placebo or active-treatment controlled trials". Lancet. 374 (9705):-
Tumilty, S. .; Munn, J. .; McDonough, S. .; Hurley, D. A.; Basford, J. R.; Baxter, G. D. (2010). "Low Level Laser Treatment of Tendinopathy:
A Systematic Review with Meta-analysis". Photomedicine and Laser Surgery. 28 (1): 3–16
321
Bjordal, J. M.; Lopes-Martins, R. A.; Joensen, J. .; Couppe, C. .; Ljunggren, A. E.; Stergioulas, A. .; Johnson, M. I. (2008). "A systematic
review with procedural assessments and meta-analysis of Low Level Laser Therapy in lateral elbow tendinopathy (tennis elbow)". BMC
Musculoskeletal Disorders. 9: 75
322
Soriano, F., et al. “Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.”
Photomedicine and Laser Therapy 24.2 (2006):-
Mantineo, Matías Eduardo Antonio. Laser therapy in inflamation: mechanisms, techniques and instrumentation. Diss. 2015.
https://estudogeral.sib.uc.pt/handle/10316/-
Choi HK. A prescription for lifestyle change in patients with hyperuricemia and gout.CurrOpinRheumatol. 2010;22(2):-
Juraschek, Stephen P., et al. "Effects of lowering glycemic index of dietary carbohydrate on plasma uric acid levels: the omnicarb randomized
clinical trial." Arthritis & Rheumatology 68.5 (2016):-
https://www.endocrine.org/topics/diabetes
327
Hardy OT, Czech MP, Corvera S. What causes the insulin resistance underlying obesity? Curr Opin Endocrinol Diabetes Obes.
2012;19(2):81-7
328
Fontaine KR, Redden DT, Wang C, et al. Years of life lost due to obesity. JAMA. 2003;289(2):-
Templeman NM, Skovso S, Page MM, et al. A causal role for hyperinsulinemia in obesity. J Endocrinol. 2017;232(3):R173-R83
330
Hansen, Merethe, et al. "Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome." Food and
chemical toxicology 46.2 (2008):-
http://pharmaxchange.info/press/2013/10/energetics-of-cellular-respiration-glucose-metabolism/
332
https://ndb.nal.usda.gov/ndb/foods/show/-
http://www.fao.org/docrep/006/y5022e/y5022e04.htm
334
https://www.diabetes.org.uk/upload/How%20we%20help/catalogue/carb-reference-list-0511.pdf
335
http://pharmaxchange.info/press/2013/10/energetics-of-cellular-respiration-glucose-metabolism/
336
https://www.washingtonpost.com/news/wonk/wp/2015/02/05/where-people-around-the-world-eat-the-most-sugar-and-fat/
337
Food and Nutrition Board (2002/2005). Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and
Amino Acids. Washington, D.C.: The National Academies Press. Page 769. ISBN-
Joint WHO/FAO expert consultation (2003). [1] (PDF). Geneva: World Health Organization. pp. 55–56. ISBN--X
339
http://www.who.int/nutrition/sugars_public_consultation/en/
340
Joint WHO/FAO expert consultation (2003). [1] (PDF). Geneva: World Health Organization. pp. 55–56. ISBN--X
341
http://www.who.int/nutrition/sugars_public_consultation/en/
342
Choi JWJ, Ford ES, Gao X, Choi HK. Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and
Nutrition Examination Survey. Arthritis Rheum. 2008b;59(1):-
Jamnik J, Rehman S,Blanco Mejia S,etal.Fructose intake and risk ofgout and hyperuricemia: asystematic review and meta-analysis of
prospectivecohort studies.BMJOpen2016;6:e013191.doi:10.1136/bmjopen-
http://www.greenmedinfo.com/article/high-fructose-corn-syrup-and-fructose-consumption-increase-risk-factors
345
Choi JWJ, Ford ES, Gao X, Choi HK. Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and
Nutrition Examination Survey. Arthritis Rheum. 2008b;59(1):-
Grygiel-Górniak, B., & Puszczewicz, M. J. (2014). Diet in hyperurykemia and gout-myths and facts. Reumatologia, 52(4), 269.
347
Sebastian A, Frassetto LA, Sellmeyer DE, et al. Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their
hominid ancestors. Amer J Clin Nutr 2002; 76:-
Kanbara A, Hakoda M, Seyama I. Urine alkalization facilitates uric acid excretion. Nutrition Journal 2010; 9: 45
349
Hagos Y, Stein D, Ugele B, et al. Human Renal Organic Anion Transporter 4 Operates as an Asymmetric Urate Transporter. J Am Soc
Nephrol 2007; 18:-
Kanbara A, Hakoda M, Seyama I. Urine alkalization facilitates uric acid excretion. Nutrition Journal 2010; 9: 45
351
Ibid
352
. Shulten P, Thomas J, Miller M, et al. The role of diet in the management of gout: a comparison of knowledge and attitudes to current
evidence. J Hum Nutr Diet 2009; 22: 3-11
REFERENCES [ pg.
353
173 ]
Kaneko, K., Aoyagi, Y., Fukuuchi, T., Inazawa, K., & Yamaoka, N. (2014). Total purine and purine base content of common foodstuffs for
facilitating nutritional therapy for gout and hyperuricemia. Biological and Pharmaceutical Bulletin, b-
Hosomi, A., Nakanishi, T., Fujita, T. & Tamai, I. (2012) Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.
PloS One 7, e-
Sutaria S, Katbamna R, Underwood M. Effectiveness of interventions for the treatment of acute and prevention of recurrent gout – a
systematic review. Rheumatology (Oxford) 2006; 45:-
Choi JW, Ford ES, Gao X, et al. Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the third national health and nutrition
examination survey. Arthritis Rheum 2008; 59:-
Dhingra R, Sullivan L, Jacques PF, et al. Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic
syndrome in middle-aged adults in the community. Circulation 2007; 116:-
Kanbara A, Hakoda M, Seyama I. Urine alkalization facilitates uric acid excretion. Nutrition Journal 2010; 9: 45.
359
Choi HK, Liu S, Curhan G. Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the third
national health and nutrition examination survey. Arthritis Rheum 2005; 52:-
Choi HK, Atkinson K, Karlson EW, et al. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 2004; 350:-
Wang WH, Chang SJ, Wang TN, et al. Complex segregation and linkage analysis of familial gout in Taiwanese aborigines. Arthritis Rheum
2004; 50:-
Choi, H. K., Atkinson, K., Karlson, E. W., Willett, W., & Curhan, G. (2004). Alcohol intake and risk of incident gout in men: a prospective
study. The Lancet,-),-
Neogi, T., Chen, C., Niu, J., Chaisson, C., Hunter, D. J., & Zhang, Y. (2014). Alcohol quantity and type on risk of recurrent gout attacks: an
internet-based case-crossover study. The American journal of medicine, 127(4),-
Kasdallah-Grissa, A., Mornagui, B., Aouani, E., Hammami, M., El May, M., Gharbi, N., ... & El-Fazaâ, S. (2007). Resveratrol, a red wine
polyphenol, attenuates ethanol-induced oxidative stress in rat liver. Life sciences, 80(11),-
Andrade, J. M. O., Frade, A. C. M., Guimarães, J. B., Freitas, K. M., Lopes, M. T. P., Guimarães, A. L. S., ... & Santos, S. H. S. (2014).
Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation
in adipose tissue of mice fed a standard diet. European journal of nutrition, 53(7),-
Lekli, I., Ray, D., & Das, D. K. (2010). Longevity nutrients resveratrol, wines and grapes. Genes & nutrition, 5(1), 55.
367
Wang, Y., Zhu, J. X., Kong, L. D., Yang, C., Cheng, C. H. K., & Zhang, X. (2004). Administration of procyanidins from grape seeds reduces
serum uric acid levels and decreases hepatic xanthine dehydrogenase/oxidase activities in oxonate-treated mice. Basic & clinical pharmacology
& toxicology, 94(5),-
Misawa, Takuma, et al. "Resveratrol inhibits the acetylated α-tubulin-mediated assembly of the NLRP3-inflammasome." International
immunology 27.9 (2015):-
Blau LW. Cherry diet control for gout and arthritis. Tex Rep Biol Med 1950; 8:-
Seeram NP, Momin RA, Nair MG, Bourquin LD. Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries.
Phytomedicine. 2001;8(5):-
Wang J, Mazza G. Inhibitory effects of anthocyanins and other phenolic compounds on nitric oxide production in LPS/ IFN-gamma-activated
RAW 264.7 macrophages. J Agric Food Chem 2002; 50:-
Schumacher Jr, H. R. (2008). The pathogenesis of gout. Cleveland Clinic journal of medicine, 75(5), S2.
373
Belcaro G, Cesarone MR, Dugall M, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended
administration in osteoarthritis patients. Altern Med Rev. 2010;15(4):-
Shakibaei M, Csaki C, Nebrichi S, Mobasheri A. Resveratrol suppresses interleukin-1β-induced inflammatory signaling and apoptosis in
human articular chondrocytes: Potential for use as a novel nutraceutical for the treatment of osteoarthritis. Biochem.Pharmacol.
2008;76(11):-
Wann AK, Mistry J, Blain EJ, Michael-Titus AT, Knight MM. Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1βmediated cartilage degradation. Arthritis Res. Ther. 2010;12(6):R207.
376
Tate GA, Mandell BF, Karmali RA, et al. Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with
gamma-linolenic acid and eicosapentaenoic acid. Arthritis Rheum. 1988;31(12):-
Choi HK. A prescription for lifestyle change in patients with hyperuricemia and gout.CurrOpinRheumatol. 2010b;22(2):-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC-/#B8
379
Childers, N. F., & Margoles, M. S. (1993). An apparent relation of nightshades (Solanaceae) to arthritis. Journal of Neurological and
Orthopaedic Medicine and Surgery, 14,-
Snaith ML. Gout: diet and uric acid revisited. Lancet 2001; 358: 525
381
Kaneko, K., Aoyagi, Y., Fukuuchi, T., Inazawa, K., & Yamaoka, N. (2014). Total purine and purine base content of common foodstuffs for
facilitating nutritional therapy for gout and hyperuricemia. Biological and Pharmaceutical Bulletin, b-
Ibid.
383
Ibid.
384
Sarwar G, Brule D. Assessment of the uricogenic potential of processed foods based on the nature and quantity of dietary purines. Prog Food
Nutr Sci 1991; 15: 159-181.
REFERENCES [ pg.
385
174 ]
Choi HK, Atkinson K, Karlson EW, et al. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 2004; 350:-
Chuang SY, Lee SC, Hsieh YT, et al. Trends in hyperuricemia and gout prevalence: Nutrition and Health Survey in Taiwan from-
to-. Asia Pac J Clin Nutr 2011; 20:-
Kaneko, K., Aoyagi, Y., Fukuuchi, T., Inazawa, K., & Yamaoka, N. (2014). Total purine and purine base content of common foodstuffs for
facilitating nutritional therapy for gout and hyperuricemia. Biological and Pharmaceutical Bulletin, b-
Grygiel-Górniak, B., & Puszczewicz, M. J. (2014). Diet in hyperurykemia and gout-myths and facts. Reumatologia, 52(4), 269.
389
Brule D, Sarwar G, Savoie L, et al. Differences in uricogenic effects of dietary purine bases, nucleosides and nucleotides in rats. J Nutr 1988;
118:-
Laguens, R. P., and CL Gomez Dumm. "Deoxyribonucleic acid synthesis in the heart mitochondria after acute and exhaustive exercise."
Experientia 24.2 (1968):-
Morgan, T. E., et al. "Effects of long-term exercise on human muscle mitochondria." Muscle metabolism during exercise. Springer, Boston,
MA,-
Holloszy, John O. "Biochemical adaptations in muscle effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in
skeletal muscle." Journal of biological chemistry 242.9 (1967):-
Pedersen, B. K. "IL-6 signalling in exercise and disease." (2007):-
Ibid.
395
Hambrecht, Rainer, et al. "Effect of exercise on coronary endothelial function in patients with coronary artery disease." New England Journal
of Medicine 342.7 (2000):-
Tomporowski, Phillip D. "Effects of acute bouts of exercise on cognition." Acta psychologica 112.3 (2003):-
Gomez-Pinilla, Fernando, Shoshanna Vaynman, and Zhe Ying. "Brain-derived neurotrophic factor functions as a metabotrophin to mediate
the effects of exercise on cognition." European Journal of Neuroscience 28.11 (2008):-
Liu-Ambrose, Teresa, and Meghan Donaldson. "Exercise and Cognition in Older Adults: Is there a Role for Resistance Training Programs?."
British journal of sports medicine (2008).
399
Nichol, Kathryn, et al. "Exercise improves cognition and hippocampal plasticity in APOE ε4 mice." Alzheimer's & Dementia 5.4 (2009):-
Petzinger, Giselle M., et al. "Enhancing neuroplasticity in the basal ganglia: the role of exercise in Parkinson's disease." Movement disorders
25.S1 (2010): S141-S145.
401
Myers, Jonathan. "Exercise and cardiovascular health." Circulation 107.1 (2003): e2-e5.
402
Rajarajeswaran, P., and R. Vishnupriya. "Exercise in cancer." Indian journal of medical and paediatric oncology: official journal of Indian
Society of Medical & Paediatric Oncology 30.2 (2009): 61.
403
American Diabetes Association. "Physical activity/exercise and diabetes mellitus." Diabetes care 26.suppl 1 (2003): s73-s77.
404.
Chipkin, Stuart & A. Klugh, Serena & Chasan-Taber, Lisa. (2001). Exercise and diabetes. Cardiology clinics-/S-
Bouchard, Claude, Jean-Pierre Depres, and Angelo Tremblay. "Exercise and obesity." Obesity research 1.2 (1993):-
Liang, Kelvin Y., et al. "Exercise and Alzheimer's disease biomarkers in cognitively normal older adults." Annals of neurology 68.3 (2010):-
Eggermont, Laura, et al. "Exercise, cognition and Alzheimer's disease: more is not necessarily better." Neuroscience & biobehavioral reviews
30.4 (2006):-
Petzinger, Giselle M., et al. "Enhancing neuroplasticity in the basal ganglia: the role of exercise in Parkinson's disease." Movement disorders
25.S1 (2010): S141-S145.
409
Reid, Kathryn J., et al. "Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia." Sleep medicine 11.9
(2010):-
Youngstedt, Shawn D., and Christopher E. Kline. "Epidemiology of exercise and sleep." Sleep and biological rhythms 4.3 (2006):-
Passos, Giselle Soares, et al. "Is exercise an alternative treatment for chronic insomnia?." Clinics 67.6 (2012):-
The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a
randomized trial.Suleen S Ho
413
Williams, Mark A., et al. "Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from
the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism." Circulation 116.5
(2007):-
Manson, JoAnn E., et al. "A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in
women." New England Journal of Medicine 341.9 (1999):-
Sjödin, Bertil, Ylva Hellsten Westing, and Fred S. Apple. "Biochemical mechanisms for oxygen free radical formation during exercise."
Sports medicine 10.4 (1990):-
David P. Swain, and Barry A. Franklin. Comparison of Cardioprotective Benefits of Vigorous Versus Moderate Intensity Aerobic
Exercise. The American Journal of Cardiology Volume 97, Issue 1, 1 January 2006, Pages-
Jonathan P. Little, Jenna B. Gillen, Michael E. Percival, Adeel Safdar, Mark A. Tarnopolsky, Zubin Punthakee, Mary E. Jung and Martin J.
Gibala. Low-volume High-intensity Interval Training Reduces Hyperglycemia and Increases Muscle Mitochondrial Capacity in Patients With
Type 2 Diabetes. J Appl Physiol 111:-, 2011.
REFERENCES [ pg.
418
175 ]
Kassia S Weston, Ulrik Wisløff, Jeff S Coombes. High-intensity Interval Training in Patients with Lifestyle-induced Cardiometabolic Disease:
a Systematic Review and Meta-analysis. Br J Sports Med 2013;0:1–9.
419
Martin J Gibala. Professor and Chair of the Kinesiology Department, McMaster University in Hamilton, Ontario. Interview conducted by
phone January 14,-
Øivind Rognmo, PhD; Trine Moholdt, PhD; Hilde Bakken, BSc; Torstein Hole, MD, PhD; Per Mølstad, MD, PhD; Nils Erling Myhr, BSc;
Jostein Grimsmo, MD, PhD; Ulrik Wisløff, PhD. Cardiovascular Risk of High- Versus Moderate-Intensity Aerobic Exercise in Coronary Heart
Disease Patients. Circulation. 2012 Sep 18;126(12):-
https://www.researchgate.net/profile/M_Feigenbaum/publication/-_Prescription_of_resistance_training_for_health_and_disease/links/
55e9f92408ae21d099c45103.pdf
422
Shellock, Frank G., and William E. Prentice. "Warming-up and stretching for improved physical performance and prevention of sports-related
injuries." Sports Medicine 2.4 (1985):-
Fradkin, Andrea J., Belinda J. Gabbe, and Peter A. Cameron. "Does warming up prevent injury in sport?: The evidence from randomised
controlled trials?." Journal of Science and Medicine in Sport 9.3 (2006):-
Fradkin, Andrea J., Tsharni R. Zazryn, and James M. Smoliga. "Effects of warming-up on physical performance: a systematic review with
meta-analysis." The Journal of Strength & Conditioning Research 24.1 (2010):-
https://www.webmd.com/arthritis/gout-attacks-at-home#2
426
Thaker PH et al. The neuroendocrine impact of chronic stress on cancer. Cell Cycle. 2007 Feb 15;6(4):-
Jacobs JR et al. Early and chronic stress and their relation to breast cancer. Psychol Med. 2000 May;30(3):-
Saul AN et al. Chronic stress and susceptibility to skin cancer. J Natl Cancer Inst. 2005 Dec 7;97(23):-
McEwen BS et al. Protective and damaging effects of stress mediators. N Engl J Med. 1998 Jan 15;338(3):-
Liu RT et al. Stress generation in depression: A systematic review of the empirical literature and recommendations for future study. Clin
Psychol Rev. 2010 Jul;30(5):582-93. Epub 2010 May 15.
431
Eiland L et al. Early life stress followed by subsequent adult chronic stresspotentiates anxiety and blunts hippocampal structural remodeling.
Hippocampus-
Saleeby, Y., Wonder Herbs: A guide to three adaptogens, Xlibris-
Servan-Schreiber D., Somatizing Patients: Part I. Practical Diagnosis., AAFP, 2000, 2:-
Mechanic D. Effects of psychological distress on perceptions of physical health and use of medical and psychiatric facilities. J Human Stress
1978; 4:-
Wolkowitz OM, Reus VI, Keebler A, et al. Double-blind treatment of major depression with dehydroepiandosterone. Am J Psychiatry
1999;156:-
Strous RD, Maayan R, Lapidus R, et al. Dehydroepiandrosterone augmentation in the management of negative, depressive, and anxiety
symptoms in schizophrenia. Arch Gen Psychiatry 2003;60:-
Wolkowitz OM, Reus VI, Manfredi F, et al. Dehydroepiandrosterone (DHEA) treatment of depression. Biol Psychiatry 1997;41:-
Sakihara S et al. Ampulla (Takotsubo) cardiomyopathy caused by secondary adrenal insufficiency in ACTH isolated deficiency. Endocr J.
2007 Aug;54(4):-
Korlakunta HL et al. Transient left ventricular apical ballooning: a novel heart syndrome. Int J Cardiol. 2005 Jul 10;102(2):-
Saleeby, Y., Wonder Herbs: A guide to three adaptogens, Xlibris-
Kondo N, Oh J. Suicide and karoshi (death from overwork) during the recent economic crisis in Japan: the impacts, mechanisms and political
responses. J Epidemiol Community Health. 2010;64(8):-
Roepke SK et al. Relationship between chronic stress and carotid intima-media thickness (IMT) in elderly Alzheimer's disease caregivers.
Stress. 2011 Jul 26.
443
Gouin JP et al. Chronic stress, daily stressors, and circulating inflammatory markers. Health Psychol. 2011 Sep 19.
444
Liu RT et al. Stress generation in depression: A systematic review of the empirical literature and recommendations for future study. Clin
Psychol Rev. 2010 Jul;30(5):-
McEwen BS. Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of
psychiatric disorders. Ann N Y Acad Sci. 2004 Dec;1032:1-7.
446
Kyrou I et al. Chronic stress, visceral obesity and gonadal dysfunction. Hormones (Athens). 2008 Oct-Dec;7(4):-
Nilsson PM et al. Sleep disturbance in association with elevated pulse rate for prediction of mortality--consequences of mental strain? J Intern
Med. 2001 Dec;250(6):-
Nielsen NR et al. Perceived stress and cause-specific mortality among men and women: results from a prospective cohort study. Am J
Epidemiol. 2008 Sep 1;168(5):481-91; discussion 92-6.
449
Brown DW, Anda RF, Tiemeier H, et al. Adverse childhood experiences and the risk of premature mortality. Am J Prev Med. 2009
Nov;37(5):-
Heraclides A et al. Psychosocial stress at work doubles the risk of type 2 diabetes in middle-aged women: evidence from the Whitehall II
study. Diabetes Care. 2009 Dec;32(12):-
Heraclides AM et al. Work Stress, Obesity and the Risk of Type 2 Diabetes: Gender-Specific Bidirectional Effect in the Whitehall II Study.
Obesity (Silver Spring). 2011 May 19.
452
Laszlo KD et al. Job strain predicts recurrent events after a first acute myocardial infarction: the Stockholm Heart Epidemiology Program. J
Intern Med. 2010 Jun;267(6):599-611.
REFERENCES [ pg.
453
176 ]
Kruk J. Self-reported psychological stress and the risk of breast cancer: A case-control study. Stress. 2011
Innes KE et al. Chronic stress and insulin resistance-related indices of cardiovascular disease risk, part I: neurophysiological responses and
pathological sequelae. Altern Ther Health Med. 2007 Jul-Aug;13(4):-
Lehrke M et al. Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute
inflammatory reactions. Crit Care. 2008;12(6):R157.
456
Siegel GJ et al. “Basic Neurochemistry; moolecular, cellular, and medical aspects”, 7th Edition. Elsvier Academic Press-
Tomlinson, J., 11β-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid., Response Endocrine Reviews,
2004, 25:-
Tak LM. Meta-analysis and meta-regression of hypothalamic-pituitary-adrenal axis activity in functional somatic disorders. Biol Phychol.
2011;87(2):-
Chrousos G., The stress response and immune function: clinical implications., Ann N Y Acad Sci, 2000;917:-
Wu, JY., Adrenal insufficiency in prolonged critical illness, Cirt Care. 2008, 12(3): R65.
461
Muneer, M. ADRENAL GLANDS published online similima.com, retrieved Aug 20,-
Sapolsky, RM, Endocrinology of the stress-response, Behavioral Endocrinology, 2nd ed. MIT, Press, Cambridge, MA, 2002 pp-
Weerth, C., Development of cortisol circadian rhythm in infancy , Early Human Development, 2003, Vol. 73, Issue 1, Pages-
Beishuizen, A., Patterns of corticosteroid--binding globulin and the free cortisol index during sepsic shock and multitrauma. Intensive Care
Med, 2001;27:-
Tomlinson, J., 11β-Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid., Response Endocrine Reviews,
2004, 25:-
Tak LM. Meta-analysis and meta-regression of hypothalamic-pituitary-adrenal axis activity in functional somatic disorders. Biol Phychol.
2011;87(2):-
Kalaitzakis E., Is fatigue related to suppression of hypothalamic-pituitary-adrenal axis activity by bile acids in chronic liver disease?, Med
Hypotheses-
Gagnon A, Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Aquat
Toxicol. 2006 10;78(1):-
Ng TB., Toxic effect of heavy metals on cells isolated from the rat adrenal and testis. In Vitro Cell Dev Biol. 1990;26(1):24-8.
470
Daugherty M et al. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem. 2002
Jun 14;277(24):-
Brandt. “The Adrenal Medulla”. Available at http://www.rosehulman.edu/~brandt/Chem330/EndocrineNotes/Chapter_4_Adrenal_Medulla.pdf Accessed 1/6/-
Veltman JC et al. Regulatory effect of copper on rat adrenal cytochrome P-450 and steroid metabolism. Biochem Pharmacol. 1986 Sep
1;35(17):-
Gagnon A, Effects of Cu on plasma cortisol and cortisol secretion by adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Aquat
Toxicol. 2006 10;78(1):-
Ng TB., Toxic effect of heavy metals on cells isolated from the rat adrenal and testis. In Vitro Cell Dev Biol. 1990;26(1):24-8.
475
Kiecolt-Glasser JK. Stress, food, and inflammation: psychoneuroimmunology andnutrition at the cutting edge. Psychosom Med. 2010
May;72(4):-
Pluess TT et al. Intravenous fish oil blunts the physiological response to endotoxin in healthy subjects. Intensive Care Med. 2007
May;33(5):-
Kiecolt-Glasser JK. Stress, food, and inflammation: psychoneuroimmunology andnutrition at the cutting edge. Psychosom Med. 2010
May;72(4):-
Head KA., Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Altern Med
Rev. 2009;14(2):-
Kalaitzakis E., Is fatigue related to suppression of hypothalamic-pituitary-adrenal axis activity by bile acids in chronic liver disease?, Med
Hypotheses-
Tak LM. Meta-analysis and meta-regression of hypothalamic-pituitary-adrenal axis activity in functional somatic disorders. Biol Phychol.
2011;87(2):-
Hertoghe, T., speech recorded at the American Academy of Anti-Aging Medicine, Las Vegas, NV,-
Wirth, M., Shiftwork duration and the awakening cortisol response among police officers., Chronobiol Int. 2011 ;28(5):-
Siddiqui, I., Serum Copper levels in various diseases: A local experience at Aga Khan University Hospital, Karachi, AKUH-
Peters EM, Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides
following ultramarathon running. Int J Sports Med. 2001 (7):-
Wu, JY., Adrenal insufficiency in prolonged critical illness, Cirt Care. 2008, 12(3): R65.
486
Ping J et al. Inheritable stimulatory effects of caffeine on steroidogenic acute regulatory protein expression and cortisol production in human
adrenocortical cells. Chem Biol Interact. 2012 Jan 5;195(1):-
Lovallo WR., Cortisol responses to mental stress, exercise, and meals following caffeine intake in men and women. Pharmacol. Biochem.
Behav. 2006 83 (3):-
Field, T., Cortisol decreases and serotonin and dopamine increase following massage therapy. The International journal of neuroscience 2005,
115 (10):-
REFERENCES [ pg.
489
177 ]
Hanley J,, Randomised controlled trial of therapeutic massage in the management of stress. Br J Gen Pract. 2003;53:20-25.
Dixit S., Executive fatigue and its management with Mentat. Pharmacopsychoecologia. 1993;6:7-9.
491
Allen K et al. Pet ownership, but not ace inhibitor therapy, blunts home blood pressure responses to mental stress. Hypertension. 2001
Oct;38(4):-
Barker SB, Wolen AR. The benefits of human-companion animal interaction: a review. J Vet Med Educ. 2008 Winter;35(4):-
Friedmann E, Son H. The human-companion animal bond: how humans benefit. Vet Clin North Am Small Anim Pract. 2009 Mar;39(2):-
Buoso E et al. Opposing effects of cortisol and dehydroepiandrosterone on the expression of the receptor for Activated C Kinase 1:
implications in immunosenescence. Exp Gerontol. 2011 Nov;46(11):-
Zaluska M et al. [Dehydroepiandrosteron (DHEA) in the mechanisms of stress and depression]. Psychiatr Pol. 2009 May-Jun;43(3):-
Ferrari E, Cravello L, et al. Age-related changes of the hypothalamic-pituitary-adrenal axis: pathophysiological correlates.Eur J Endocrinol .
2001 Apr;144(4):-
Rasmuson S, Näsman B, Calström K, et el. Increased levels of adrenocortical and gonadal hormones in mild to moderate Alzheimer’s disease.
Dement Geriatr Cogn Disord. 2002;13(2):74-9.
498
Barrett-Connor, E., A Prospective Study of Dehydroepiandrosterone Sulfate, Mortality, and Cardiovascular Disease, N Engl J Med 1986;
315:-
Feldman HA, Johannes CB, et al. Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: cross-sectional results from the
Massachusetts Male Aging Study. Ann Epidemiol . 1998 May;8(4):-
Shufelt, C., DHEA-S levels and cardiovascular disease mortality in postmenopausal women: results from the National Institutes of Health-National Heart, Lung, and Blood Institute (NHLBI)-sponsored Women's Ischemia Syndrome Evaluation (WISE). J Clin Endocrinol Metab. 2010
Nov;95(11):-
Lasco A., Metabolic effects of dehydroepiandrosterone replacement therapy in postmenopausal women.Eur J Endocrinol . 2001
Oct;145(4):-
Villareal DT. Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. JAMA . 2004
Nov 10;292(18):-
Ferrari E., Cognitive and affective disorders in the elderly: a neuroendocrine study. Arch Gerontol Geriatr Suppl . 2004;(9):-
van Broekhoven F., Neurosteroids in depression: a review. Psychopharmacology (Berl) . 2003 Jan;165(2):-
Schmidt PJ., DHEA monotherapy in midlife-onset and minor depression. Arch Gen Psychiatry. 2005 Feb;62(2):-
Dhatariya K, Bigelow ML, et al. Effect of DHEA replacement on insulin sensitivity and lipids in hypoadrenal women.Diabetes . 2005
Mar;54(3):-
Kameda W, Daimon M, et al. Association of decrease in serum DHEA-S levels with the progression to type 2 diabetes in men of a Japanese
population: the Funagata study. Metabolism . 2005 May;54(5):-
Ciolino H., Dehydroepiandrosterone inhibits the expression of carcinogen-activating enzymes in vivo. Int J Cancer 2003;105:-
Villareal DT., Effects of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf)
2000;53:-
Presman DM et al. Melatonin inhibits glucocorticoid-dependent GR-TIF2 interaction in newborn hamster kidney (BHK) cells. Mol Cell
Endocrinol. 2012 Feb 26;349(2):214-21. Epub 2011 Nov 4.
511
James FO et al. Circadian rhythms of melatonin, cortisol, and clock gene expression during simulated night shift work. Sleep. 2007
Nov;30(11):-
Hertoghe, T., speech recorded at the American Academy of Anti-Aging Medicine, Las Vegas, NV,-
Pawlikowski M., Effects of six months melatonin treatment on sleep quality and serum concentrations of estradiol, cortisol,
dehydroepiandrosterone sulfate, and somatomedin C in elderly women. Neuroendocrinol Lett. 2002;23 Suppl 1:-
Bruls E.,Melatonin. I. Physiology of its secretion]. Rev Med Liege. 2000 Aug;55(8):-
Soszynski P., Decreased melatonin concentration in Cushing's syndrome., Horm Metab Res. 1989;21(12):-
Reiter RJ,. Melatonin: an antioxidant in edible plants. Ann N Y Acad Sci. 2002 May;957:-
Pawlikowski M., Effects of six months melatonin treatment on sleep quality and serum concentrations of estradiol, cortisol,
dehydroepiandrosterone sulfate, and somatomedin C in elderly women. Neuroendocrinol Lett. 2002;23 Suppl 1:-
Soszynski P., Decreased melatonin concentration in Cushing's syndrome., Horm Metab Res. 1989;21(12):-
Bruls E.,Melatonin. I. Physiology of its secretion]. Rev Med Liege. 2000 Aug;55(8):-
Tahiliani AG, Beinlich CJ. Pantothenic acid in health and disease. Vitam Horm. 1991;46:-
Plesofsky-Vig N., Pantothenic acid. In: Shils ME, eds. Modern Nutrition in Health and Disease, 8th ed. Malvern, PA: Lea & Febiger,-
Calcium pantothenate in arthritic conditions. A report from the General Practitioner Research Group. Practitioner 1980;224:-
Webster MJ., Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives. Eur J Appl Physiol
Occup Physiol 1998;77:-
Berg AL et al. The effects of adrenocorticotrophic hormone and cortisol on homocysteine and vitamin B concentrations. Clin Chem Lab Med.
2006;44(5):-
Morfin R., (ed), DHEA and the Brain; Vol. 1, Taylor & Francis, NY,-
Bornstein SR. Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla. Endocr Res. 2004 Nov;30(4):-
REFERENCES [ pg.
527
178 ]
Brody S., A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to
psychological stress.Psychopharmacology (Berl). 2002;159:-
Carroll D. The effects of an oral multivitamin combination with calcium, magnesium, and zinc on psychological well-being in healthy young
male volunteers: a double-blind, placebo-controlled trial. Psychopharmacology (Berl). 2000;150:-
Evans J, Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis, Eye.2008 Jun;
22(6):-
Hemila H. Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress. Int J Sports Med
1996;17:-
Eipper BA., The biosynthesis of neuropeptides: peptide alpha-amidation. Annu Rev Neurosci(1992). 15:-
Peters EM, Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides
following ultramarathon running. Int J Sports Med. 2001 (7):-
Carroll D. The effects of an oral multivitamin combination with calcium, magnesium, and zinc on psychological well-being in healthy young
male volunteers: a double-blind, placebo-controlled trial. Psychopharmacology (Berl). 2000;150:-
Kobayashi A. Trace element and hormonal responses during flight aptitude test. Aviat Space Environ Med. 1996;67(4):-
Schulz V., Rational Phytotherapy: A Physicians' Guide to Herbal Medicine. 3rd ed. Berlin, Germany: Springer-Verlag; 1998:271, 273.
536
Wilborn, D., Effects of Zinc Magnesium Aspartate (ZMA) Supplementation on Training Adaptations and Markers of Anabolism and
Catabolism., Journal of the International Society of Sports Nutrition 2004;1 (2):-
Golf, Sw., On the significance of magnesium in extreme physical stress. Cardiovascular drugs and therapy / sponsored by the International
Society of Cardiovascular Pharmacotherapy. 1998, 12 2 (2suppl):-
Nathan PJ, Lu K, Gray M, Oliver C. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive
enhancing agent. J Herb Pharmacother. 2006;6(2):-
Vuong QV, Bowyer MC, Roach PD. L-theanine: properties, synthesis and isolation from tea. J Sci Food Agric. 2011a Aug 30;91(11):-
Wakabayashi C, Numakawa T, Ninomiya M, Chiba S, Kunugi H. Behavioral and molecular evidence for psychotropic effects in L: -theanine.
Psychopharmacology (Berl)-
Cho HS, Kim S, Lee SY, Park JA, Kim SJ, Chun HS. Protective effect of the green tea component, L-theanine on environmental toxinsinduced neuronal cell death. Neurotoxicology. 2008 Jul;29(4):-
Nagasawa K, Aoki H, Yasuda E, Nagai K, Shimohama S, Fujimoto S. Possible involvement of group I mGluRs in neuroprotective effect of
theanine. Biochem Biophys Res Commun. 2004 Jul 16;320(1):-
Di X, Yan J, Zhao Y, et al. L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced
excitotoxicity via inhibition of the NMDA receptor pathway. Neuroscience. 2010 Jul 14;168(3):-
Kakuda T. Neuroprotective effects of the green tea components theanine and catechins. Biol Pharm Bull. 2002 Dec;25(12):-
Dimpfel W, Kler A, Kriesl E, Lehnfeld R, Keplinger-Dimpfel IK. Source density analysis of the human EEG after ingestion of a drink
containing decaffeinated extract of green tea enriched with L-theanine and theogallin. Nutr Neurosci. 2007 Jun-Aug;10(3-4):-
Heese T, Jenkinson J, Love C, et al. Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male
Sprague-Dawley rat. AANA J. 2009 Dec;77(6):-
Yin C, Gou L, Liu Y, et al. Antidepressant-like Effects of L-theanine in the Forced Swim and Tail Suspension Tests in Mice. Phytother Res.
2011 Mar 21.
548
Dimpfel W, Kler A, Kriesl E, Lehnfeld R, Keplinger-Dimpfel IK. Source density analysis of the human EEG after ingestion of a drink
containing decaffeinated extract of green tea enriched with L-theanine and theogallin. Nutr Neurosci. 2007 Jun-Aug;10(3-4):-
Dimpfel W, Kler A, Kriesl E, Lehnfeld R. Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: I.
electrophysiological characterization in the rat hippocampus in-vitro. J Pharm Pharmacol. 2007 Aug;59(8):-
Dimpfel W, Kler A, Kriesl E, Lehnfeld R, Keplinger-Dimpfel IK. Source density analysis of the human EEG after ingestion of a drink
containing decaffeinated extract of green tea enriched with L-theanine and theogallin. Nutr Neurosci. 2007a Jun-Aug;10(3-4):-
Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008;17 Suppl
1:-
Gomez-Ramirez M, Kelly SP, Montesi JL, Foxe JJ. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial
attention task. Brain Topogr. 2009 Jun;22(1):-
Bradbury J., An adaptogenic role for omega-3 fatty acids in stress; a randomised placebo controlled double blind intervention study (pilot).
Nutr J. 2004 11: 28.
554
Delarue J., Fish oil prevents the adrenal activation elicited by mental stress in healthy men. Diabetes Metab. 2003 Jun;29(3):-
Maes M,. Decreased dehydroepiandrosterone sulfate but normal insulin-like growth factor in chronic fatigue syndrome (CFS): relevance for
the inflammatory response in CFS. Neuro Endocrinol Lett. 2005;26(5):-
Puri BK. Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). J Clin
Pathol. 2007;60(2):-
Warren G,. The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids
(EFA) and a placebo-controlled treatment study with high dose of EFA. Acta Neurol Scand. 1999;99(2):-
Hidalgo C., Effect of the lipid environment on protein motion and enzymatic activity of the sacroplasmic reticulum calcium ATPase, J Biol
Chem 1978; 253:-
Hirata F., Phospholipid methylation and biological signal transmission. Science, 1980;209:-.
REFERENCES [ pg.
560
179 ]
Willis AL., Nutritional and pharmacologic factors in eicosanoid biology. Nutr Rev 1981; 39:289-301.
Silvers KM., Randomised double-blind placebo-controlled trial of fish oil in the treatment of depression. Prostaglandins Leukot Essent Fatty
Acids. 2005;72:-
Logan, A. Omega-3 fatty acids and major depression: A primer for the mental health professional. Lipids Health Dis. 2004; 3: 25.
563
Araujo DM., What is the effectiveness of the use of polyunsaturated fatty acid omega-3 in the treatment of depression? Expert Rev Neurother.
2010; 10(7):-
Forsythe P, Kunze WA. Voices from within: gut microbes and the CNS. Cellular and molecular life sciences: CMLS.Jan 2013;70(1):-
Foster JA, Lyte M, Meyer E, Cryan JF. Gut microbiota and brain function: An evolving field in neuroscience. The international journal of
neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP).Oct-
Dinan TG, Cryan JF. Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology.
Psychoneuroendocrinology.Sep 2012;37(9):-
Forsythe P, Kunze WA. Voices from within: gut microbes and the CNS. Cellular and molecular life sciences: CMLS.Jan 2013;70(1):-
Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev
Neurosci.2012;13(10):-
Petra AI, Panagiotidou S, Hatziagelaki E, Stewart JM, Conti P, Theoharides TC. Gut-Microbiota-Brain Axis and Its Effect on
Neuropsychiatric Disorders With Suspected Immune Dysregulation. Clinical therapeutics.May 1 2015;37(5):-
Sanders ME. Probiotics: Definition, Sources, Selection, and Uses. Clinical Infectious Diseases.February 1,-;46(Supplement 2):S58S61.
571
Lalonde R, Violle N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and
Bifidobacterium longum R0175) in rats and human subjects. The British journal of nutrition.Mar 2011;105(5):-
Gareau MG, Jury J, MacQueen G, Sherman PM, Perdue MH. Probiotic treatment of rat pups normalises corticosterone release and ameliorates
colonic dysfunction induced by maternal separation. Gut.Nov 2007;56(11):-
Bravo JA, Forsythe P, Chew MV, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression
in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences of the United States of America. Sep 20 2011;108(38):-
Lalonde R, Violle N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and
Bifidobacterium longum R0175) in rats and human subjects. The British journal of nutrition.Mar 2011;105(5):-
Arseneault-Breard J, Rondeau I, Gilbert K, Girard SA, Tompkins TA, Godbout R, Rousseau G. Combination of Lactobacillus helveticus
R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat
model. The British journal of nutrition.Jun 2012;107(12):-
Violle N, Bisson JF, Desor D, Javelot H, Rougeot C. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus
R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes. Jul-Aug 2011;2(4):-
Messaoudi M, Lalonde R, Violle N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus
R0052 and Bifidobacterium longum R0175) in rats and human subjects. The British journal of nutrition.Mar 2011;105(5):-
Calcaterra NE, Barrow JC. Classics in chemical neuroscience: diazepam (valium). ACS chemical neuroscience.Apr 16 2014;5(4):-
Messaoudi M, Lalonde R, Violle N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus
R0052 and Bifidobacterium longum R0175) in rats and human subjects. The British journal of nutrition.Mar 2011;105(5):-
Messaoudi M, Violle N, Bisson JF, Desor D, Javelot H, Rougeot C. Beneficial psychological effects of a probiotic formulation (Lactobacillus
helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes. Jul-Aug 2011;2(4):-
Methlie P et al. Grapefruit juice and licorice increase cortisol availability in patients with Addison's disease. Eur J Endocrinol. 2011
Nov;165(5):-
Schambelan M., Licorice ingestion and blood pressure regulating hormones., Steroids.1994;59(2):-
Kennedy DO., Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytother
Res. 2006 Feb;20(2):-
Kennedy DO., Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom
Med. 2004 Jul;66(4):-
Dimpfel W, Kler A, Kriesl E, Lehnfeld R, Keplinger-Dimpfel IK. Source density analysis of the human EEG after ingestion of a drink
containing decaffeinated extract of green tea enriched with L-theanine and theogallin. Nutr Neurosci. 2007 Jun-Aug;10(3-4):-
Dimpfel W, Kler A, Kriesl E, Lehnfeld R. Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: I.
electrophysiological characterization in the rat hippocampus in-vitro. J Pharm Pharmacol. 2007b Aug;59(8):-
Cases J et al. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders
and sleep disturbances. Med J Nutrition Metab. 2011 Dec;4(3):-
Kelly GS. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev. 2001 Jun;6(3):-
Lipnick RL, Filov VA. Nikolai Vasilyevich Lazarev, toxicologist and pharmacologist, comes in from the cold. Trends Pharmacol Sci. 1992
Feb;13(2):-
Brekhman II, Dardymov IV. New substances of plant origin which increase nonspecific resistance. Annu Rev Pharmacol. 1969;9:-
Saleeby, Y., Wonder Herbs: A guide to three adaptogens, Xlibris-
Brekhman II., Pharmacological investigation of glycosides from Ginseng and Eleutherococcus.Lloydia. 1969;32:-
Saleeby, Y., Wonder Herbs: A guide to three adaptogens, Xlibris-
REFERENCES [ pg.
594
180 ]
Spasov AA., A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the
fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000 Apr;7(2):-
Gaffney BT.,The effects of Eleutherococcus senticosus and Panax ginseng on steroidal hormone indices of stress and lymphocyte subset
numbers in endurance athletes. Life Sci.2001;70:-
Kelly GS. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev. 2001 Jun;6(3):-
Panossian A., Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.,
Phytother Res. 2005;19(10):-
Shevtsov VA, A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental
work. Phytomedicine. 2003 Mar;10(2-3):-
Spasov AA., A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the
fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000 Apr;7(2):-
De Bock K, Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab. 2004;14(3):-
Olsson EM et al. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of
Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):-
Panossian A, Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin
Pharmacol. 2009 Sep;4(3):-
Spasov AA., A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the
fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine. 2000 Apr;7(2):-
van Diermen D, Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. 2009;122(2):-
Stancheva SL, Effect of the extract of Rhodiola rosea L. on the content of the brain biogenic monamines. Med Physiol 1987;40:-
Olsson EM et al. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of
Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):-
Mishra LC, Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev. 2000 Aug;5(4):-
Tohda C, Search for natural products related to regeneration of the neuronal network. Neurosignals. 2005;14(1-2):-
Cooley K, Naturopathic Care for Anxiety: A Randomized Controlled Trial ISRCTN-. PLoS ONE 2009; 4(8): e-
Choudhary MI., Cholinesterase inhibiting withanolides from Withania somnifera. Chem Pharm Bull, 2004;52(11):-
Sheikh N, Ahmad A, Siripurapu KB, et al. Effect of Bacopa monniera on stress induced changes in plasma corticosterone and brain
monoamines in rats. J Ethnopharmacol. 2007;111(3):-
Auddy B et al. A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans:
A Double-Blind, Randomized, Placebo-controlled Study. 2008; 11(1):-
Chen JK., Chinese Medical Herbology and Pharmacology, CA: Art of Medicine Press;-
Huang KC. The Pharmacology of Chinese Herbs, 2nd ed. New York: CRC Press;-
Chan TWD., Differentiation and Authentication of Panax ginseng, Panax quinquefolius, and Ginseng Products by Using HPCL/MS,
Analytical Chemistry, 2000; 72 (10),-
Davydov M, Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. Journal of
Ethnopharmacology 2000; 72(3):-
Ma SW, Benzie IF, Chu TT, et al. Effect of Panax ginseng supplementation on biomarkers of glucose tolerance, antioxidant status and
oxidative stress in type 2 diabetic subjects: results of a placebo-controlled human intervention trial. Diabetes Obes Metab. 2008
Nov;10(11):-
Barton, DL., Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dosefinding evaluation: NCCTG trial N03CA. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in
Cancer 2010;18 (2):-
Wang J, Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng. J Ethnopharmacol. 2010; 20;130(2):-
Amin KA, Awad EM, Nagy MA. Effects of panax quinquefolium on streptozotocin-induced diabetic rats: role of C-peptide, nitric oxide and
oxidative stress. Int J Clin Exp Med. 2011;4(2):-
Cao Y, Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running. J
Ethnopharmacol. 2011 Aug 22.
622
Liu L, Effects of ginsenosides on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor in rats exposed to chronic
unpredictable mild stress. Zhongguo Zhong Yao Za Zhi. 2011;36(10):-
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J
Oncol. 2012;-
Mcmahon M, Gerich J, Rizza R. Effects of glucocorticoids on carbohydrate metabolism. Diabetes/Metabolism Reviews. 1988;4(1):-
Grover JK, Yadav S, Vats V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol. 2002;81(1):-
Gupta P, Yadav DK, Siripurapu KB, et al. Constituents of Ocimum sanctum with antistress activity. J Nat Prod. 2007;70(9):-
Mondal S, Varma S, Bamola VD, et al. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum
Linn.) leaf extract on healthy volunteers. J Ethnopharmacol. 2011;136(3):-
Bhattacharyya D, Sur TK, Jana U, et al. Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorders. Nepal Med
Coll J. 2008;10(3):-
Ibid.
REFERENCES [ pg.
181 ]
630
Bhattacharya SK, Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study. Phytomedicine.
1998;5(2):-
Sheikh N, Ahmad A, Siripurapu KB, et al. Effect of Bacopa monniera on stress induced changes in plasma corticosterone and brain
monoamines in rats. J Ethnopharmacol. 2007;111(3):-
Head KA., Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Altern Med
Rev. 2009;14(2):-
Stough CK, Pase MP, Cropley V, et al. A randomized controlled trial investigating the effect of Pycnogenol and Bacopa CDRI08 herbal
medicines on cognitive, cardiovascular, and biochemical functioning in cognitively healthy elderly people: the Australian Research Council
Longevity Intervention (ARCLI) study protocol (ANZCTR-). Nutr J. 2012;11:11.
634
Li SP, Zhao KJ, Ji ZN, et al. A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against
hydrogen peroxide-induced injury. Life Sci. 2003;73(19):-
Koh JH, Kim KM, Kim JM, et al. Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis. Biol Pharm
Bull. 2003;26(5):-
Ibid.
637
Kiho T, Ookubo K, Usui S, et al. Structural features and hypoglycemic activity of a polysaccharide (CS-F10) from the cultured mycelium of
Cordyceps sinensis. Biol Pharm Bull. 1999;22(9):-
Leu SF, Chien CH, Tseng CY, et al. The in vivo effect of Cordyceps sinensis mycelium on plasma corticosterone level in male mouse. Biol
Pharm Bull. 2005;28(9):-
Nagata A, Tajima T, Uchida M. Supplemental anti-fatigue effects of Cordyceps sinensis (tochu-kaso) extract powder during three stepwise
exercise of human. Jpn J Phys Fitness Sports Med. 2005;55 Suppl.:S-
Anderson DC. Assessment and nutraceutical management of stress-induced adrenal dysfunction. Integrative Medicine. 2008;7(5):18-25.
Sun LJ, Wang GH, Wu B, et al. [Effects of schisandra on the function of the pituitary-adrenal cortex, gonadal axis and carbohydrate
metabolism in rats undergoing experimental chronic psychological stress, navigation and strenuous exercise]. Zhonghua Nan Ke Xue.
2009;15(2):-
Panossian A. Adaptogens. Tonic herbs for fatiuge and stress. Altern Complement Ther. 2003;9(6):-
Zhang J, Ma RC et al. Relationship of Sleep Quantity and Quality with 24-Hour Urinary Catecholamines and Salivary Awakening Cortisol in
Healthy Middle-Aged Adults. Sleep, 2011; 34(2):-
Bonnet MH and Arand DL. Hyperarousal and Insomnia: State of the Science. Sleep Medicine Reviews, 2010;14:9-15
645
Butcher SK, Killampalli V, Lascelles D, et al. Raised cortisol:DHEAS ratios in the elderly after injury: potential impact upon neutrophil
function and immunity. Aging Cell. 2005 4(6):-
Chiodini I, Scillitani A. Role of cortisol hypersecretion in the pathogenesis of osteoporosis. RecentiProg Med-):-
Duong M, Cohen JI, and Convit A. h cortisol levels are associated with low quality food choice in type 2 diabetes. Endocrine-):-
Irwin MR, Wang M et al. Sleep Deprivation and Activation of Morning Levels of Cellular and Genomic Markers of Inflammation. Archives
of Internal Medicine, 2006; 166:-
Smith MT, Quartana PJ et al. Mechanisms By Which Sleep Disturbance Contributes to Osteoarthritic Pain: A Conceptual Model. Current Pain
and Headache Reports, 2009; 13:-
UAB News. [Lollar J.] Sleep debt hikes risk of stroke symptoms despite healthy BMI. 6/11/2012 Available at:
http://www.uab.edu/news/latest/item/2483-sleep-debt-hikes-risk-of-stroke-symptoms-despite-healthy-bmi?tmpl=component&print=1
651
Chien KL, Chen PC, Hsu HC, et al. Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report
from a community-based cohort. Sleep-):-
Hublin C, Partinen M, Koskenvuo M, et al. Heritability and mortality risk of insomnia-related symptoms: a genetic epidemiologic study in a
population-based twin cohort. Sleep-):-
http://news.harvard.edu/gazette/story/2011/01/eight-weeks-to-a-better-brain
654
http://www.ahc.umn.edu/img/assets/20825/MindfulnessADHD-Zylowska_et_al.pdf
655 Z Bai, J Chang, C Chen, P Li, K Yang and I Chi. (2015). “Investigating the effect of transcendental meditation on blood pressure: a
systematic review and meta-analysis”, Journal of Human Hypertension.
656
Brook, Robert D. et al., “Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure. A Scientific Statement from the
American Heart Association”, published on April 22,-
http://tmhome.com/wp-content/uploads/2012/07/Study-on-stress-reduction-and-mortality.pdf
658
Duraimani S, Schneider RH, Randall OS, Nidich SI, Xu S, Ketete M, et al. (2015) “Effects of Lifestyle Modification on Telomerase Gene
Expression in Hypertensive Patients: A Pilot Trial of Stress Reduction and Health Education Programs in African Americans.” PLOS ONE
10(11): e-. doi:10.1371/journal.pone-
http://gretchenrubin.com/happiness_project/2011/01/six-questions-to-help-you-keep-your-cool-instead-of-losing-your-temper/
641
Kanbara A, Hakoda M, Seyama I. Urine alkalization facilitates uric acid excretion. Nutrition Journal
2010; 9: 45
REFERENCES [ pg.
182 ]
The Journal of clinical investigation
The Journal of Clinical Endocrinology & Metabolism
Tasevska, Nataša, et al. "Sugars in diet and risk of cancer in the NIHInternational journal of cancer
International journal of oncology
Nephrology
Dialysis Transplantation
International journal of obesity
British
journal of nutrition
Experimental and clinical endocrinology & diabetes
Carcinogenesis
Pharmacology
Fiziolohichnyi zhurnal (Kiev, Ukraine: 1994)
Atherosclerosis
Regulatory peptides
Biochemistry
Pharmacology Biochemistry and Behavior
Journal of Endocrinology
American Journal of PhysiologyRenal Physiology
κB
European journal of pharmacology
Autonomic Neuroscience
Cancer research
Carbohydrate Research
Expert opinion on therapeutic targets
International
journal of endocrinology
Adeva-Andany, M. M., Fernández-Fernández, C., Mouriño-Bayolo, D., Castro-Quintela, E., &
Domínguez-Montero, A. (2014). Sodium bicarbonate therapy in patients with metabolic acidosis.
The Scientific World Journal, 2014.
1
Mo S-F, Zhou F, Lv Y-Z, et al. Hypouricemic action of selected flavonoids in mice: structure-activity relationships. Biol. Pharm. Bull.
2007;30(8):-
Hu QH, Wang C, Li JM, Zhang DM, Kong LD. Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced
by fructose intake: renal organic ion transporter involvement. AJP: Renal Physiology. 2009;297(4):F1080–F1091.
REFERENCES [ pg.
3
Wang Y, Zhu JX et al. Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine
dehydrogenase/oxidase activities in oxonate-treated mice. Basic ClinPharmacolToxicol. 2004 May;94(5):232-7.
183 ]